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中华重症医学电子杂志 ›› 2017, Vol. 03 ›› Issue (03): 208 -213. doi: 10.3877/cma.j.issn.2096-1537.2017.03.011

所属专题: 重症医学 文献资源库

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重度急性胰腺炎的连续性肾替代治疗:合并或未合并急性肾损伤
蒋怡佳 1, 李文雄 1 , ( )   
  1. 1. 100020 北京,首都医科大学附属北京朝阳医院SICU
  • 收稿日期:2016-12-28 出版日期:2017-08-28
  • 通信作者: 李文雄
  • 基金资助:
    首都卫生发展科研专项(首发2014-2-2031)

Continuous renal replacement therapy in severe acute pancreatitis patients: with or without acute kidney injury

Yijia Jiang 1, Wenxiong Li 1 , ( )   

  1. 1. Department of Surgical Intensive Care Unit, Beijing Chaoyang Hospital, Beijing 100020, China
  • Received:2016-12-28 Published:2017-08-28
  • Corresponding author: Wenxiong Li
  • About author:
    Corresponding author: Li Wenxiong, Email:

重度急性胰腺炎(SAP)是一种起病急、进展快、并发症多、病死率高的全身炎症反应性疾病。由于连续性肾替代治疗(CRRT)具有清除炎症因子的作用,在国内越来越多的SAP患者接受了CRRT,无论其是否伴有急性肾损伤(AKI)。本文就CRRT技术治疗SAP的病理生理学基础、炎症因子清除效果和临床疗效作一综述,以期临床能够更理性地认识CRRT对SAP的治疗价值。另外,本文还展望了集成血液净化技术治疗SAP的发展前景。

Severe acute pancreatitis (SAP) is a systemic inflammatory disease characterized by sudden occurrence, complications and high mortality. Since continuous renal replacement therapy (CRRT) has a role in the removal of inflammatory cytokines, a growing number of SAP patients in China have received CRRT, regardless of whether the patient with acute kidney injury (AKI) or not. In this review, we talk about the pathophysiology, inflammatory factor clearance and clinical effect of CRRT in SAP in order to give a rational understanding of its therapeutic value. In addition, the prospects of hybrid blood purification technology in SAP treatment are also discussed.

表1 连续性肾替代治疗清除重度急性胰腺炎患者血浆炎症因子的研究
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