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中华重症医学电子杂志 doi: 10.3877/cma.j.issn.2096-1537.2024.12.30-0006

综述

重症患者肌肉减少症评估方法的研究进展
陈湘锭1, 任衍康1, 张文辉1, 左祥荣1, 曹权1,()   
  1. 1.210029 江苏南京,南京医科大学第一附属医院重症医学科
  • 收稿日期:2024-05-07
  • 通信作者: 曹权
  • 基金资助:
    江苏省333人才工程项目(2022-3-25-045)江苏省青年医学人才项目(QNRC2016557)江苏省高层次卫生人才“六个一工程”拔尖人才工程项目(LGY2019067)

Research update on evaluation methods of sarcopenia in critically ill patients

Xiangding Chen1, Yankang Ren1, Wenhui Zhang1, Xiangrong Zuo1, Quan Cao1,()   

  1. 1.Department of Critical Care Medicine, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
  • Received:2024-05-07
  • Corresponding author: Quan Cao
引用本文:

陈湘锭, 任衍康, 张文辉, 左祥荣, 曹权. 重症患者肌肉减少症评估方法的研究进展[J/OL]. 中华重症医学电子杂志, doi: 10.3877/cma.j.issn.2096-1537.2024.12.30-0006.

Xiangding Chen, Yankang Ren, Wenhui Zhang, Xiangrong Zuo, Quan Cao. Research update on evaluation methods of sarcopenia in critically ill patients[J/OL]. Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition), doi: 10.3877/cma.j.issn.2096-1537.2024.12.30-0006.

肌肉减少症(Sarcopenia),简称肌少症,是以骨骼肌质量、力量逐渐全面丧失为特征的病症,有诸多不良的临床结局。肌少症在ICU患者中也是非常普遍的存在,常导致多种不良预后,逐渐引起ICU医师的重视。肌少症可实现的评估方法包括肌力测量、体能表现评估和肌肉数量或质量的测量。肌力测量和体能表现评估在ICU患者中可行性太小,故对重症患者进行肌少症评估时,多测量肌肉的质量或数量,目前主要的评估方法包括双能X射线(DXA)、生物电阻抗分析(BIA)、CT、磁共振(MRI)、超声(US)、肌少症指数(SI)等多种方法,每个方法各有其特点,对于重症患者来说,也各有其优劣势。本文就相关研究作一综述,以期为重症患者的肌少症临床评估和科学研究提供参考。

Sarcopenia is a syndrome characterized by progressive and generalized loss of skeletal muscle mass and strength. It is associated with numerous negative clinical consequences. Patients in the ICU are more likely to develop this syndrome, which associates with various adverse outcomes. This syndrome is gathering more and more attention among intensivists. The diagnosis of sarcopenia is generally based on low muscle mass and either low muscle strength or low physical performance. The feasibility of assessing muscle strength and physical performance in critically ill patients may be inappropriate. Therefore, when evaluating ICU patients with sarcopenia, it is more appropriate to focus on the muscle mass. Various methods can be employed, including dualenergy X-ray absorptiometry (DXA), bioelectrical impedance analysis (BIA), computed tomography (CT), magnetic resonance imaging (MRI), ultrasonography (US), sarcopenia index (SI), and other techniques. Each method has its own characteristics, advantages and disadvantages for critically ill patients. This article reviewed the relevant studies in order to provide necessary references for the clinical evaluation and scientific research of sarcopenia in critically ill patients.

表1 ICU肌少症各项评估技术的比较
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