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中华重症医学电子杂志 ›› 2016, Vol. 02 ›› Issue (03) : 171 -174. doi: 10.3877/cma.j.jssn.2096-1537.2016.03.007

所属专题: 重症医学 文献

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免疫功能抑制患者的血行性感染:临床处理有何不同?
杜斌   
  • 收稿日期:2016-07-11 出版日期:2016-08-28
  • 通信作者: 杜斌
  • 基金资助:
    首都特色临床应用研究专项基金(Z131107002213112)

Management of bloodstream infection in immunocompromised patients

Bin Du   

  • Received:2016-07-11 Published:2016-08-28
  • Corresponding author: Bin Du
  • About author:
    Corresponding author: Du Bin, Email:
引用本文:

杜斌. 免疫功能抑制患者的血行性感染:临床处理有何不同?[J]. 中华重症医学电子杂志, 2016, 02(03): 171-174.

Bin Du. Management of bloodstream infection in immunocompromised patients[J]. Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition), 2016, 02(03): 171-174.

血行性感染是免疫功能抑制患者最常见的感染性并发症之一,罹患率和致死率很高。革兰阴性杆菌(尤其多重耐药革兰阴性杆菌)是最常见的致病微生物。由于免疫功能抑制患者炎症反应减弱,血行性感染的临床表现缺乏特异度,往往需要结合生物标志物进行综合判断。免疫功能抑制患者发生血行性感染后,其抗生素治疗疗程应适当延长。

Bloodstream infection (BSI) is one of the major infectious complications in immunocompromised patients, leading to high morbidity and mortality. Gram-negative bacilli, especially those multi-resistant strains are the most common pathogens seen in this cohort of patients. Due to the insufficient inflammatory response, there is a lack of specific clinical manifestations of BSI in immunocompromised patients and therefore identification of biomarkers is required to help clinical diagnosis. A prolonged duration of antibiotic therapy should be considered in immunocompromised patients with BSI.

表1 免疫功能抑制的定义
表2 MASCC风险模型:根据患者出现发热时的表现给予相应分数*
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