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中华重症医学电子杂志 ›› 2017, Vol. 03 ›› Issue (02) : 143 -147. doi: 10.3877/cma.j.issn.2096-1537.2017.02.013

所属专题: 文献

综述

急性肾损伤的流行病学研究进展
闻英1, 席修明1,()   
  1. 1. 100038 首都医科大学附属复兴医院重症医学科
  • 收稿日期:2016-12-30 出版日期:2017-05-28
  • 通信作者: 席修明
  • 基金资助:
    首都特色临床医学应用发展项目综合ICU急性肾损伤的流行病学研究(D101100050010058)

Recent progress in epidemiologic research of acute kidney injury

Ying Wen1, Xiuming Xi1,()   

  1. 1. Department of Critical Care Medicine, Fuxing Hospital, Capital Medical University, Beijing 100038, China
  • Received:2016-12-30 Published:2017-05-28
  • Corresponding author: Xiuming Xi
  • About author:
    Corresponding author: Xi Xiuming, Email:
引用本文:

闻英, 席修明. 急性肾损伤的流行病学研究进展[J/OL]. 中华重症医学电子杂志, 2017, 03(02): 143-147.

Ying Wen, Xiuming Xi. Recent progress in epidemiologic research of acute kidney injury[J/OL]. Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition), 2017, 03(02): 143-147.

急性肾损伤(AKI)是影响许多人健康的重要疾病,常伴随多种并发症。近年急性肾损伤的发病率明显升高,每年约1300万人发生急性肾损伤(其中发展中国家的患者占85%),约170万人死于急性肾损伤及其并发症。Meta分析显示全球成人住院患者急性肾损伤的发生率为21.6%,我国住院患者急性肾损伤的发生率为0.99%~11.6%。重症医学科患者急性肾损伤的发病率及病死率高于普通病房,远期预后差。不同研究报道的急性肾损伤发病率差异很大。目前,国外高收入国家的流行病学研究多为多中心、大样本研究,很多数据来源于大型数据库,但前瞻性研究并不多见;中低收入国家高水平的研究报道较少。近年我国急性肾损伤流行病学研究取得了很大进展,并受到重视。

Acute kidney injury (AKI) has been recognized as a major healthcare problem affecting millions of patients worldwide, and is associated with a substantial increase in morbidity and mortality. AKI occurs in about 13.3 million people per year, 85% of whom live in the developing world, is thought to contribute to about 1.7 million deaths every year. A meta-analysis showed that the incidence of AKI was 21.6% in adult hospitalized patients worldwide and the incidence was 0.99%-11.6% in China. The incidence and mortality of AKI patients in intensive care unit are higher than general ward, with a poor long-term prognosis. The epidemiological results of AKI varies widely among studies. Overall, epidemiological results of AKI in high income countries of multicenter, large sample studies are from large databases, but lack of prospective studies. There are few high quality studies of AKI in the low and middle income countries. In recent years, great progress has been made in epidemiological studies in china.

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