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中华重症医学电子杂志 ›› 2020, Vol. 06 ›› Issue (02) : 143 -145. doi: 10.3877/cma.j.issn.2096-1537.2020.02.007

所属专题: 重症营养 重症医学 文献

专题笔谈

急性胃肠损伤与重症心脏疾病的关系
张李迪1, 陈德昌1,()   
  1. 1. 200025 上海交通大学医学院附属瑞金医院重症医学科
  • 收稿日期:2020-05-13 出版日期:2020-05-28
  • 通信作者: 陈德昌
  • 基金资助:
    国家自然科学基金项目(81571943, 81873944)

Acute gastrointestinal injury and cardiovascular disease

Lidi Zhang1, Dechang Chen1,()   

  1. 1. Department of Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
  • Received:2020-05-13 Published:2020-05-28
  • Corresponding author: Dechang Chen
  • About author:
    Corresponding author: Chen Dechang, Email:
引用本文:

张李迪, 陈德昌. 急性胃肠损伤与重症心脏疾病的关系[J]. 中华重症医学电子杂志, 2020, 06(02): 143-145.

Lidi Zhang, Dechang Chen. Acute gastrointestinal injury and cardiovascular disease[J]. Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition), 2020, 06(02): 143-145.

胃肠道是重症患者应激的中心器官和多器官功能障碍综合征的启动器官。急性胃肠损伤时肠黏膜屏障破坏,同时肠道微环境改变引起肠道菌群紊乱,肠道细菌和毒素大量移位,诱发和加重全身炎症反应,导致包括心血管系统在内的多器官功能障碍。本文就肠与心交互作用的相关研究进展进行综述。

The gastrointestinal tract is the central organ of stress, and it is the initially involved organ of the multiple organ dysfunction syndrome. When acute gastrointestinal injury occurs, the gut mucosal barrier is damaged and the intestinal flora is also altered due to the change of gut microenvironment, which together leads to bacterial translocation and endotoxemia, and thus induces and exacerbates systemic inflammatory response syndrome, ultimately resulting in multiple organ dysfunction, including the cardiovascular system. This article reviews the progress in the understanding of the relationship between acute gastrointestinal injury and cardiovascular disease.

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