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中华重症医学电子杂志 ›› 2021, Vol. 07 ›› Issue (01) : 1 -5. doi: 10.3877/cma.j.issn.2096-1537.2021.01.001

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关注SARS-CoV-2致病机制的研究
刘军1,()   
  1. 1. 215001 南京医科大学姑苏学院,苏州市立医院,南京医科大学附属苏州医院ICU
  • 收稿日期:2020-02-28 出版日期:2021-02-28
  • 通信作者: 刘军

Unraveling the pathogenesis of severe acute respiratory syndrome coronavirus 2

Jun Liu1,()   

  1. 1. Department of Critical Care Medicine, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School of Nanjing Medical University, Suzhou 215001, China
  • Received:2020-02-28 Published:2021-02-28
  • Corresponding author: Jun Liu
引用本文:

刘军. 关注SARS-CoV-2致病机制的研究[J]. 中华重症医学电子杂志, 2021, 07(01): 1-5.

Jun Liu. Unraveling the pathogenesis of severe acute respiratory syndrome coronavirus 2[J]. Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition), 2021, 07(01): 1-5.

严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)传染性强,可导致患者出现严重急性呼吸道感染(SARI)和多器官系统功能损害。SARS-CoV-2致病机制尚不明确,推测免疫炎症反应紊乱在其发生发展中发挥至关重要的作用。结合相关领域的研究进展,梳理SARS-CoV-2可能的致病机制,厘清未来研究方向,具有重要临床意义。

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly contagious and can lead to severe acute respiratory tract infection (SARI) and multiple organ dysfunction. The pathogenesis of SARS-CoV-2 is unclear. Accordingly, we speculate that dysregulated immune response plays a crucial role in the mechanisms of SARS-CoV-2 pathogenesis. It is of great clinical and reserch significance to clarify the possible pathogenesis of SARS-CoV-2 .

图1 SARS-CoV-2致病机制示意图
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