1 |
Laird DW, Lampe PD. Therapeutic strategies targeting connexins [J]. Nat Rev Drug Discov, 2018, 17(12): 905-921.
|
2 |
Dbouk HA, Mroue RM, El-Sabban ME, et al. Connexins: a myriad of functions extending beyond assembly of gap junction channels [J]. Cell Commun Signal, 2009, 7: 4.
|
3 |
Rodjakovic D, Salm L, Beldi G. Function of Connexin-43 in macrophages [J]. Int J Mol Sci, 2021, 22(3): 1412.
|
4 |
Saez JC, Berthoud VM, Branes MC, et al. Plasma membrane channels formed by connexins: their regulation and functions [J]. Physiol Rev, 2003, 83(4): 1359-1400.
|
5 |
Kar R, Batra N, Riquelme MA, et al. Biological role of connexin intercellular channels and hemichannels [J]. Arch Biochem Biophys, 2012, 524(1): 2-15.
|
6 |
Zhang Q, Bai X, Liu Y, et al. Current concepts and perspectives on Connexin43: a mini review [J]. Curr Protein Pept Sci, 2018, 19(11): 1049-1057.
|
7 |
Martins-Marques T, Ribeiro-Rodrigues T, Batista-Almeida D, et al. Biological functions of Connexin43 beyond intercellular communication [J]. Trends Cell Biol, 2019, 29(10): 835-847.
|
8 |
Nagata K, Masumoto K, Esumi G, et al. Connexin43 plays an important role in lung development [J]. J Pediatr Surg, 2009, 44(12): 2296-2301.
|
9 |
Cai Q, Zhao X, Yu X, et al. The specific Connexin 43-inhibiting peptide gap26 improved alveolar development of neonatal rats with hyperoxia exposure [J]. Front Pharmacol, 2021, 12: 587267.
|
10 |
Johnson LN, Koval M. Cross-talk between pulmonary injury, oxidant stress, and gap junctional communication [J]. Antioxid Redox Signal, 2009, 11(2): 355-367.
|
11 |
Wright JR. The "wisdom" of lung surfactant: balancing host defense and surface tension-reducing functions [J]. Am J Physiol Lung Cell Mol Physiol, 2006, 291(5): L847-850.
|
12 |
Kasper M, Traub O, Reimann T, et al. Upregulation of gap junction protein connexin43 in alveolar epithelial cells of rats with radiation-induced pulmonary fibrosis [J]. Histochem Cell Biol, 1996, 106(4): 419-424.
|
13 |
O'Donnell JJ,3rd, Birukova AA, Beyer EC, et al. Gap junction protein connexin43 exacerbates lung vascular permeability [J]. PLoS One, 2014, 9(6): e100931.
|
14 |
Fanelli V, Ranieri VM. Mechanisms and clinical consequences of acute lung injury [J]. Ann Am Thorac Soc, 2015, 12(Suppl 1): S3-8.
|
15 |
Parthasarathi K. Endothelial connexin43 mediates acid-induced increases in pulmonary microvascular permeability [J]. Am J Physiol Lung Cell Mol Physiol, 2012, 303(1): L33-42.
|
16 |
Liu T, Li Y, Zhang B, et al. The role of phosphorylated Cx43 on PKC mediated Ser368 in lung injury induced by seawater inhalation [J]. Inflammation, 2015, 38(5): 1847-1854.
|
17 |
Zhou J, Fu Y, Liu K, et al. miR-206 regulates alveolar type Ⅱ epithelial cell Cx43 expression in sepsis-induced acute lung injury [J]. Exp Ther Med, 2019, 18(1): 296-304.
|
18 |
赵希伟, 周佳伟, 刘凯, 等. 连接蛋白43通过蛋白激酶A介导丝氨酸373调控脓毒症急性肺损伤肺泡Ⅱ型上皮细胞屏障功能的研究 [J/OL]. 中华危重症医学杂志(电子版), 2021, 14(5): 355-361.
|
19 |
Wang S, Sun Y, Bai Y, et al. Contribution of connexin hemichannels to the pathogenesis of acute lung injury [J]. Mediators Inflamm, 2020, 2020: 8094347.
|
20 |
Parthasarathi K, Ichimura H, Monma E, et al. Connexin 43 mediates spread of Ca2+-dependent proinflammatory responses in lung capillaries [J]. J Clin Invest, 2006, 116(8): 2193-2200.
|
21 |
Yao Y, Zeng QX, Deng XQ, et al. Connexin 43 upregulation in mouse lungs during ovalbumin-induced asthma [J]. PLoS One, 2015, 10(12): e0144106.
|
22 |
Paw M, Borek I, Wnuk D, et al. Connexin43 controls the myofibroblastic differentiation of bronchial fibroblasts from patients with asthma [J]. Am J Respir Cell Mol Biol, 2017, 57(1): 100-110.
|
23 |
Huang JQ, Chen XY, Huang F, et al. Effects of Connexin 43 Inhibition in an Ovalbumin-induced mouse model of asthma [J]. Iran J Allergy Asthma Immunol, 2018, 17(1): 29-38.
|
24 |
Billaud M, Dahan D, Marthan R, et al. Role of the gap junctions in the contractile response to agonists in pulmonary artery from two rat models of pulmonary hypertension [J]. Respir Res, 2011, 12(1): 30.
|
25 |
Chen M, Liu Y, Yi D, et al. Tanshinone ⅡA promotes pulmonary artery smooth muscle cell apoptosis in vitro by inhibiting the JAK2/STAT3 signaling pathway [J]. Cell Physiol Biochem, 2014, 33(4): 1130-1138.
|
26 |
Han XJ, Zhang WF, Wang Q, et al. HIF-1α promotes the proliferation and migration of pulmonary arterial smooth muscle cells via activation of Cx43 [J]. J Cell Mol Med, 2021, 25(22): 10663-10673.
|
27 |
Qin X, Hou X, Xu X, et al. Down-regulation of connexin 43 contributes to structure and function of pulmonary artery in nicotine-administered mice [J]. Toxicol Lett, 2023, 377: 1-13.
|
28 |
Zhang LΖ, Fan ZR, Wang L, et al. Carbenoxolone decreases monocrotaline‑induced pulmonary inflammation and pulmonary arteriolar remodeling in rats by decreasing the expression of connexins in T lymphocytes [J]. Int J Mol Med, 2020, 45(1): 81-92.
|
29 |
Boengler K, Rohrbach S, Weissmann N, et al. Importance of Cx43 for right ventricular function [J]. Int J Mol Sci, 2021, 22(3): 987.
|
30 |
Zang JP, Wei R. Effects of Cx43 gene modification on the proliferation and migration of the human lung squamous carcinoma cell line NCI-H226 [J]. Genet Mol Res, 2015, 14(4): 13110-13119.
|
31 |
Xu HT, Li QC, Zhang YX, et al. Connexin 43 recruits E-cadherin expression and inhibits the malignant behaviour of lung cancer cells [J]. Folia Histochem Cytobiol, 2008, 46(3): 315-321.
|
32 |
Zhao W, Han HB, Zhang ZQ. Suppression of lung cancer cell invasion and metastasis by Connexin43 involves the secretion of follistatin-like 1 mediated via histone acetylation [J]. Int J Biochem Cell Biol, 2011, 43(10): 1459-1468.
|
33 |
Ruch RJ. Connexin43 suppresses lung cancer stem cells [J]. Cancers (Basel), 2019, 11(2): 175.
|
34 |
Huang W, Wang Y, He T, et al. Arteannuin B enhances the effectiveness of Cisplatin in non-small cell lung cancer by regulating Connexin 43 and MAPK pathway [J]. Am J Chin Med, 2022, 50(7): 1963-1992.
|
35 |
Jones JC, Bodenstine TM. Connexins and glucose metabolism in cancer [J]. Int J Mol Sci, 2022, 23(17): 10172.
|
36 |
Luo M, Luo Y, Mao N, et al. Cancer-associated fibroblasts accelerate malignant progression of non-small cell lung cancer via Connexin 43-formed unidirectional gap junctional intercellular communication [J]. Cell Physiol Biochem, 2018, 51(1): 315-336.
|
37 |
Ni C, Lou X, Yao X, et al. ZIP1+ fibroblasts protect lung cancer against chemotherapy via connexin-43 mediated intercellular Zn2+ transfer [J]. Nat Commun, 2022, 13(1): 5919.
|
38 |
Cooreman A, Caufriez A, Tabernilla A, et al. Effects of drugs formerly proposed for COVID-19 treatment on Connexin43 hemichannels [J]. Int J Mol Sci, 2022, 23(9): 5018.
|
39 |
Eltzschig HK, Eckle T, Mager A, et al. ATP release from activated neutrophils occurs via connexin 43 and modulates adenosine-dependent endothelial cell function [J]. Circ Res, 2006, 99(10): 1100-1108.
|
40 |
Swartzendruber JA, Nicholson BJ, Murthy AK. The role of Connexin 43 in lung disease [J]. Life (Basel), 2020, 10(12): 363.
|
41 |
Peirouvi T, Aliaghaei A, Eslami Farsani B, et al. COVID-19 disrupts the blood-testis barrier through the induction of inflammatory cytokines and disruption of junctional proteins [J]. Inflamm Res, 2021, 70(10-12): 1165-1175.
|
42 |
Li MW, Mruk DD, Lee WM, et al. Connexin 43 is critical to maintain the homeostasis of the blood-testis barrier via its effects on tight junction reassembly [J]. Proc Natl Acad Sci U S A, 2010, 107(42): 17998-18003.
|
43 |
Machtaler S, Dang-Lawson M, Choi K, et al. The gap junction protein Cx43 regulates B-lymphocyte spreading and adhesion [J]. J Cell Sci, 2011, 124(Pt 15): 2611-2621.
|
44 |
Machtaler S, Choi K, Dang-Lawson M, et al. The role of the gap junction protein connexin43 in B lymphocyte motility and migration [J]. FEBS Lett, 2014, 588(8): 1249-1258.
|
45 |
Huang Y, Mao Z, Zhang Z, et al. Connexin43 contributes to inflammasome activation and lipopolysaccharide-initiated acute renal injury via modulation of intracellular oxidative status [J]. Antioxid Redox Signal, 2019, 31(16): 1194-1212.
|
46 |
Neijssen J, Pang B, Neefjes J. Gap junction-mediated intercellular communication in the immune system [J]. Prog Biophys Mol Biol, 2007, 94(1-2): 207-218.
|
47 |
Matsue H, Yao J, Matsue K, et al. Gap junction-mediated intercellular communication between dendritic cells (DCs) is required for effective activation of DCs [J]. J Immunol, 2006, 176(1): 181-190.
|
48 |
Feng YY, Tang M, Suzuki M, et al. Essential role of NADPH oxidase-dependent production of reactive oxygen species in maintenance of sustained B cell receptor signaling and B cell proliferation [J]. J Immunol, 2019, 202(9): 2546-2557.
|
49 |
Huang Y, Mao Z, Zhang X, et al. Connexin43 is required for the effective activation of spleen cells and immunoglobulin production [J]. Int J Mol Sci, 2019, 20(22): 5789.
|
50 |
Yao Y, Fan XL, Jiang D, et al. Connexin 43-mediated mitochondrial transfer of iPSC-MSCs alleviates asthma inflammation [J]. Stem Cell Reports, 2018, 11(5): 1120-1135.
|
51 |
Li X, Zhang Y, Yeung SC, et al. Mitochondrial transfer of induced pluripotent stem cell-derived mesenchymal stem cells to airway epithelial cells attenuates cigarette smoke-induced damage [J]. Am J Respir Cell Mol Biol, 2014, 51(3): 455-465.
|
52 |
Boengler K, Leybaert L, Ruiz-Meana M, et al. Connexin 43 in mitochondria: what do we really know about its function? [J]. Front Physiol, 2022, 13: 928934.
|