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中华重症医学电子杂志 ›› 2016, Vol. 02 ›› Issue (04) : 240 -243. doi: 10.3877/cma.j.issn.2096-1537.2016.04.003

所属专题: 重症医学 文献

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高流量氧疗:临床值得关注的问题
庄金强1, 潘纯1, 杨毅1,()   
  1. 1. 210009 南京,东南大学附属中大医院重症医学科
  • 收稿日期:2016-10-26 出版日期:2016-11-28
  • 通信作者: 杨毅
  • 基金资助:
    江苏省临床医学科技专项(BL2013030); 国家自然基金(81300043)

High-flow nasal cannula: need to be concerned

Jinqiang Zhuang1, Chun Pan1, Yi Yang1,()   

  1. 1. Department of Critical Care Medicine, Zhongda Hospital, Southeast University, Nanjing 210009, China
  • Received:2016-10-26 Published:2016-11-28
  • Corresponding author: Yi Yang
  • About author:
    Corresponding author: Yang Yi, Email:
引用本文:

庄金强, 潘纯, 杨毅. 高流量氧疗:临床值得关注的问题[J]. 中华重症医学电子杂志, 2016, 02(04): 240-243.

Jinqiang Zhuang, Chun Pan, Yi Yang. High-flow nasal cannula: need to be concerned[J]. Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition), 2016, 02(04): 240-243.

急性呼吸衰竭是以低氧血症为特征的急性呼吸功能障碍,是威胁重症患者生命的常见疾病。机械通气是纠正严重低氧血症的主要措施,随着经鼻高流量氧疗(high flow nasal cannula, HFNC)技术的不断进步,由于其具有无创、减少口鼻咽部解剖死腔、呼气末正压通气(positive end-expiratory pressure,PEEP)效应、增加呼气末肺容积和改善舒适度等优点,逐渐在临床上成为治疗呼吸衰竭的重要手段,但由于HFNC的适应证、PEEP样效应、HFNC相关性肺损伤的发生及有创通气的转换时机等问题尚不明确,需要临床医师密切关注。

Acute respiratory failure is characterized by an acute onset of hypoxemia with a high morbidiity and mortality rate in critically ill patients. Although mechanical ventilation is still the mainstay therapy for severe hypoxiemia, with the technical progress in high-flow nasal cannula (HFNC), the latter has been widely applied to the acute respiratory failure patients because of its physiological effects: reduction of anatomical dead space, delivering a positive end expiratory pressure (PEEP) effects, increasing end-expiratory lung volume and a better comfortness. However, it still needs to be concerned about the indication, the exact PEEP effect, HFNC associated lung injury and the timing of mechanical ventilation when treating acute respiratory falure patients with HFNC.

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