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中华重症医学电子杂志 ›› 2016, Vol. 02 ›› Issue (04) : 269 -272. doi: 10.3877/cma.j.issn.2096-1537.2016.04.010

所属专题: 重症医学 文献

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急性呼吸窘迫综合征:我选择有创机械通气
章志丹1,()   
  1. 1. 110001 沈阳,中国医科大学附属第一医院重症医学科
  • 收稿日期:2016-11-09 出版日期:2016-11-28
  • 通信作者: 章志丹
  • 基金资助:
    辽宁省自然科学基金(2014021078)

To treat acute respiratory distress syndrom: I prefer invasive mechanical ventilation

Zhidan Zhang1,()   

  1. 1. Department of Critical Care Medicine, The First Affiliated Hospital of China Medical University, Shenyang 110001, China
  • Received:2016-11-09 Published:2016-11-28
  • Corresponding author: Zhidan Zhang
  • About author:
    Corresponding author: Zhang Zhidan, Email:
引用本文:

章志丹. 急性呼吸窘迫综合征:我选择有创机械通气[J]. 中华重症医学电子杂志, 2016, 02(04): 269-272.

Zhidan Zhang. To treat acute respiratory distress syndrom: I prefer invasive mechanical ventilation[J]. Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition), 2016, 02(04): 269-272.

急性呼吸窘迫综合征(acute respiratory distress syndrom,ARDS)是一种急性低氧性呼吸衰竭,在重症患者中具有较高的发病率和病死率。肺泡塌陷和肺内分流增加是ARDS主要的病理生理机制。如何有效地开放塌陷的肺泡、降低肺内分流以及改善氧合是ARDS治疗的首要目标。研究显示,小潮气量、高呼气末正压(positive end-expiratory pressure,PEEP)水平、俯卧位通气以及神经肌肉阻滞剂的应用等有创机械通气手段能够显著降低ARDS患者的病死率。因此,对于ARDS的治疗,我选择有创机械通气。

ARDS is an acute hypoxemic respiratory failure, which has a high morbidity and mortarlity rate among critically ill patients. The collapse of alveoli and an increased intrapulmonary shunt are prominent pathophysiology of ARDS.How to recruit the collapsed alveoli and decrease intrapulmonary shunt so as to improve oxygenation are the main targets of ARDS treatment. The use of low tidal volume ventilation, higher PEEP level, prone positioning and neuromuscular blocking agents in mechanical ventilated ARDS patients have been proved effective in decreasing ARDS mortality. So, we prefer to use invasive mechanical ventilation to treat ARDS.

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