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中华重症医学电子杂志 ›› 2022, Vol. 08 ›› Issue (01) : 55 -61. doi: 10.3877/cma.j.issn.2096-1537.2022.01.008

综述

功能残气量在重症患者中的应用进展
刘学松1, 刘晓青1, 黎毅敏1,()   
  1. 1. 510120 呼吸疾病国家重点实验室 广州呼吸健康研究院 广州医科大学附属第一医院重症医学科
  • 收稿日期:2021-09-14 出版日期:2022-02-28
  • 通信作者: 黎毅敏
  • 基金资助:
    广东省科技计划项目(2020B1111340001); 广州医科大学附属第一医院培育项目

Application of functional residual capacity in critically ill patients

Xuesong Liu1, Xiaoqing Liu1, Yimin Li1,()   

  1. 1. Department of Critical Care Medicine, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Disease, State Key Laboratory of Respiratory Diseases, Guangzhou 510120, China
  • Received:2021-09-14 Published:2022-02-28
  • Corresponding author: Yimin Li
引用本文:

刘学松, 刘晓青, 黎毅敏. 功能残气量在重症患者中的应用进展[J/OL]. 中华重症医学电子杂志, 2022, 08(01): 55-61.

Xuesong Liu, Xiaoqing Liu, Yimin Li. Application of functional residual capacity in critically ill patients[J/OL]. Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition), 2022, 08(01): 55-61.

功能残气量(FRC)是平静呼气末肺内残留的气体量,具有重要的生理功能。在需要机械通气的重症患者中呼气结束时的肺容积被称为呼气末肺容积。目前临床上有多种检测和监测FRC的方法,包括CT测量法、氦气稀释法、氮气冲洗法、电阻抗断层成像技术等方法,其中氮气冲洗法中的氮气洗入/洗出技术更适合在重症患者中开展。FRC可以作为评估机械通气患者肺部疾病病情并指导个性化的保护性机械通气策略的方法,来降低呼吸机相关性肺损伤(VILI)。FRC在机械通气患者中的临床应用越来越受到重视,在病情评估、ARDS患者中的肺保护通气设置和麻醉时肺部情况监测等方面具有重要临床意义。本文对FRC的病理生理功能、检测方法及在重症患者中的应用进行综述。

Functional residual capacity (FRC) is the amount of residual air in the lungs at the end of expiration calm, which has important physiological functions. In critically ill patients requiring mechanical ventilation, the lung volume at the end of expiration is called the end-expiratory lung volume. There are many clinical methods for detecting and monitoring FRC, including CT measurement, helium dilution, nitrogen flushing, electrical impedance tomography and other methods. Among them, the nitrogen flushing in/out technology in the nitrogen flushing method is easy to being. carried out in critically ill patients. FRC can be used to assess the condition of lung diseases in mechanically ventilated patients and guide the designation of personalized protective mechanical ventilation strategies to reduce ventilator-induced lung injury. More and more attention is paid to the clinical application of FRC in mechanically ventilated patients, which is of great significance in terms of disease assessment, lung protection ventilation settings for ARDS patients, and lung condition monitoring during anesthesia. This article reviews the pathophysiological functions, detection methods and application of FRC in critically ill patients.

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