| 1 |
Cajander S，Kox M，Scicluna BP，et al.Profiling the dysregulated immune response in sepsis：overcoming challenges to achieve the goal of precision medicine ［J］.Lancet Respir Med，2024，12（4）：305-322.
|
| 2 |
Rudd KE，Johnson SC，Agesa KM，et al.Global，regional，and national sepsis incidence and mortality，1990-2017：analysis for the global burden of disease study ［J］.Lancet，2020，395（10219）：200-211.
|
| 3 |
Cavaillon JM，Singer M，Skirecki T，Sepsis therapies：learning from 30 years of failure of translational research to propose new leads ［J］.EMBO Mol Med，2020，12（4）：e10128.
|
| 4 |
Udit S，Blake K，Chiu IM.Somatosensory and autonomic neuronal regulation of the immune response ［J］.Nat Rev Neurosci，2022，23（3）：157-171.
|
| 5 |
Chu C，Artis D，Chiu IM，Neuro-immune interactions in the tissues ［J］.Immunity，2020，52（3）：464-474.
|
| 6 |
Liu S，Wang ZF，Su YS，et al.Somatotopic organization and intensity dependence in driving distinct NPY-expressing sympathetic pathways by electroacupuncture ［J］.Neuron，2020，108（3）：1-39.
|
| 7 |
Caravaca AS，Gallina AL，Tarnawski L，et al.Vagus nerve stimulation promotes resolution of inflammation by a mechanism that involves Alox15 and requires the α7nAChR subunit ［J］.Proc Natl Acad Sci U S A，2022，119（22）：e2023285119.
|
| 8 |
Jin H，Li M，Jeong E，et al.A body-brain circuit that regulates body inflammatory responses ［J］.Nature，2024，630（8017）：695-703.
|
| 9 |
Liu S，Wang Z，Su Y，et al.A neuroanatomical basis for electroacupuncture to drive the vagal-adrenal axis ［J］.Nature，2021，598（7882）：641-645.
|
| 10 |
Manabe T，Heneka MT，Cerebral dysfunctions caused by sepsis during ageing ［J］.Nat Rev Immunol，2022，22（7）：444-458.
|
| 11 |
Huang X，Wei P，Fang C，et al.Compromised endothelial Wnt/betacatenin signaling mediates the blood-brain barrier disruption and leads to neuroinflammation in endotoxemia ［J］.J Neuroinflammation，2024，21（1）：265.
|
| 12 |
Wei C，Jiang W，Wang R，et al.Brain endothelial GSDMD activation mediates inflammatory BBB breakdown ［J］.Nature，2024，629（8013）：893-900.
|
| 13 |
Hoogland ICM，Yik J，Westhoff D，et al.Microglial cell response in α7 nicotinic acetylcholine receptor-deficient mice after systemic infection with Escherichia coli ［J］.J Neuroinflammation，2022，19（1）：94.
|
| 14 |
Yin L，Zhang J，Ma H，et al.Selective activation of cholinergic neurotransmission from the medial septal nucleus to hippocampal pyramidal neurones improves sepsis-induced cognitive deficits in mice［J］.Br J Anaesth，2023，130（5）：573-584.
|
| 15 |
Villareal JAB，Bathe T，Hery GP，et al.Deterioration of neuroimmune homeostasis in Alzheimer’s disease patients who survive a COVID-19 infection ［J］.J Neuroinflammation，2024，21（1）：202.
|
| 16 |
Grant RA，Poor TA，Sichizya L，et al.Prolonged exposure to lungderived cytokines is associated with activation of microglia in patients with COVID-19 ［J］.JCI Insight，2024，9（8）：e178859.
|
| 17 |
Luo RY，Luo C，Zhong F，et al.ProBDNF promotes sepsis-associated encephalopathy in mice by dampening the immune activity of meningeal CD4+ T cells ［J］.J Neuroinflammation，2020，17（1）：169.
|
| 18 |
Sinha P，Kerchberger VE，Willmore A，et al.Identifying molecular phenotypes in sepsis：an analysis of two prospective observational cohorts and secondary analysis of two randomised controlled trials ［J］.Lancet Respir Med，2023，11（11）：965-974.
|
| 19 |
Joshi PR，Adhikari S，Onah C，et al.Lung-innervating nociceptor sensory neurons promote pneumonic sepsis during carbapenemresistant Klebsiella pneumoniae lung infection ［J］.Science Advances，2024，10（36）：eadl6162.
|
| 20 |
Hollenberg SM，Singer M，Pathophysiology of sepsis-induced cardiomyopathy ［J］.Nat Rev Cardiol，2021，18（6）：424-434.
|
| 21 |
Zhao Y，Zang B，Wang Q.The effectiveness of alkaline phosphatase in sepsis-associated acute kidney injury ［J］.Intensive Care Med，2024，50（5）：778-780.
|
| 22 |
Steiner SE，Choong FX，Antypas H，et al.UPEC kidney infection triggers neuro-immune communication leading to modulation of local renal inflammation by splenic IFNγ ［J］.PLoS Pathog，2021，17（5）：e1009553.
|
| 23 |
Sun J，Zhang J，Wang X，et al.Gut-liver crosstalk in sepsis-induced liver injury ［J］.Crit Care，2020，24（1）：614.
|
| 24 |
Maiwall R，Kulkarni AV，Arab JP，et al.Acute liver failure ［J］.Lancet，2024，404（10454）：789-802.
|
| 25 |
Körner A，Schlegel M，Kaussen T，et al.Sympathetic nervous system controls resolution of inflammation via regulation of repulsive guidance molecule A ［J］.Nat Commun，2019，10（1）：633.
|
| 26 |
Oami T，Abtahi S，Shimazui T，et al.Claudin-2 upregulation enhances intestinal permeability，immune activation，dysbiosis，and mortality in sepsis ［J］.Proc Natl Acad Sci U S A，2024，121（10）：e2217877121.
|
| 27 |
Zhang X，Liu H，Hashimoto K，et al.The gut-liver axis in sepsis：interaction mechanisms and therapeutic potential ［J］.Crit Care，2022，26（1）：213.
|
| 28 |
Lai NY，Musser MA，Pinho-Ribeiro FA，et al.Gut-innervating nociceptor neurons regulate Peyer’s patch microfold cells and SFB levels to mediate salmonella host defense ［J］.Cell，2020，180（1）：33-49.e22.
|
| 29 |
Nagashima H，Mahlakõiv T，Shih HY，et al.Neuropeptide CGRP limits group 2 innate lymphoid cell responses and constrains type 2 inflammation ［J］.Immunity，2019，51（4）：682-695.e6.
|
| 30 |
Seillet C，Luong K，Tellier J，et al.The neuropeptide VIP confers anticipatory mucosal immunity by regulating ILC3 activity ［J］.Nat Immunol，2020，21（2）：168-177.
|
| 31 |
Jarret A，Jackson R，Duizer C，et al.Enteric nervous system-derived IL-18 orchestrates mucosal barrier immunity ［J］.Cell，2020，180（1）：1-38.
|