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中华重症医学电子杂志 ›› 2015, Vol. 01 ›› Issue (01) : 39 -41. doi: 10.3877/cma.j.jssn.2096-1537.2015.01.010

所属专题: 重症医学 文献 指南共识

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重症感染:准确诊断是规范抗生素治疗的前提
杜斌1,*,*   
  1. 1. 100730,中国医学科学院北京协和医院内科ICU
  • 收稿日期:2015-07-02 出版日期:2015-11-28
  • 通信作者: 杜斌

Severe sepsis: appropriate antibiotic therapy depends upon correct diagnosis

Bin Du1   

  1. 1. Medical ICU, Peking Union Medical College Hospital, Beijing 100032, China
  • Received:2015-07-02 Published:2015-11-28
  • Corresponding author: Bin Du
  • About author:
    Corresponding author: Du Bin, Email: dubin98@gmail.com
引用本文:

杜斌. 重症感染:准确诊断是规范抗生素治疗的前提[J]. 中华重症医学电子杂志, 2015, 01(01): 39-41.

Bin Du. Severe sepsis: appropriate antibiotic therapy depends upon correct diagnosis[J]. Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition), 2015, 01(01): 39-41.

重症感染是危重病患者死亡的主要原因。正确的经验性抗生素治疗能够改善重症感染患者的临床预后。非感染性炎症反应与感染的准确鉴别需要综合考虑临床表现、实验室检查、微生物学结果以及生物学标志物。应当根据感染的特点包括感染部位选择经验性抗生素,而不应盲目依赖广谱抗生素。临床医生应当重视感染灶的控制。

Severe sepsis is the major cause of death in critically ill patients, while appropriate empirical antibiotic therapy might improve clinical outcome in patients with severe sepsis. Differential diagnosis of non-infectious inflammation and sepsis requires integration of clinical manifestation, laboratory investigation including microbiologic results, and biomarkers. Choice of empirical antibiotics should be based on characteristics of infection, including focus of infection. Source control is also crucial in the treatment of severe sepsis.

表1 检验前概率对降钙素原鉴别细菌感染准确性的影响(%)[6]
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