How the change of acute kidney injury diagnostic criteria influence its clinical therapy?

doi:10.3877/cma.j.issn.2096-1537.2017.01.003

Abstract

Abstract:

Acute kidney injury (AKI) is paid a rising attention due to its high mortality. During 10 years from 2002 to 2012, it′s the diagnostic criteria was changed from RIFLE, AKIN to KDIGO criteria. With the change of AKI diagnostic criteria, the clinicians have better understanding and much more meticulous regulation in hemodynamic monitoring, nutritional support, anticoagulation, renal replacement therapy (RRT) model selection

Key words: Acute kidney injury, Diagnosis, differential, Clinical protocols

Hongliang Wang, Ruijin Liu, Kaijiang Yu. How the change of acute kidney injury diagnostic criteria influence its clinical therapy?[J]. Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition), 2017, 03(01): 5-8.

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URL: https://icu.cma-cmc.com.cn/EN/10.3877/cma.j.issn.2096-1537.2017.01.003

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References 17

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分级	Scr或GFR	尿量与时间
危险（risk）	Scr上升至超过原来的1.5倍，或GFR下降>25%	<0.5 ml/（kg?h），>6 h
损伤（injury）	Scr上升至超过原来的2倍，或GFR下降>25%	<0.5 ml/（kg?h），>12 h
衰竭（failure）	Scr上升至超过原来的3倍或GFR下降>75%，Scr≥354 μmol/L，或急性增加≥44 μmol/L	<0.3 ml/（kg?h），>24 h，或无尿>12 h
肾功能丧失（loss）	持续肾衰竭超过4周
终末期肾病（ESRD）	持续肾衰竭超过3个月

分级	Scr或GFR	尿量与时间
危险（risk）	Scr上升至超过原来的1.5倍，或GFR下降>25%	<0.5 ml/（kg?h），>6 h
损伤（injury）	Scr上升至超过原来的2倍，或GFR下降>25%	<0.5 ml/（kg?h），>12 h
衰竭（failure）	Scr上升至超过原来的3倍或GFR下降>75%，Scr≥354 μmol/L，或急性增加≥44 μmol/L	<0.3 ml/（kg?h），>24 h，或无尿>12 h
肾功能丧失（loss）	持续肾衰竭超过4周
终末期肾病（ESRD）	持续肾衰竭超过3个月

分期	Scr	尿量与时间
1期	Scr值增加≥26.4 μmol/L，或增至Scr值基线的1.5~2.0倍	<0.5 ml/（kg?h），>6 h
2期	Scr值增至基线的2.0~3.0倍	<0.5 ml/（kg?h），>12 h
3期	Scr值增至基线的3.0倍以上，或Scr值≥354 μmol/L，或急性Scr值增加≥44 μmol/L	<0.3 ml/（kg?h），>24 h，或无尿>12 h

分期	Scr	尿量与时间
1期	Scr值增加≥26.4 μmol/L，或增至Scr值基线的1.5~2.0倍	<0.5 ml/（kg?h），>6 h
2期	Scr值增至基线的2.0~3.0倍	<0.5 ml/（kg?h），>12 h
3期	Scr值增至基线的3.0倍以上，或Scr值≥354 μmol/L，或急性Scr值增加≥44 μmol/L	<0.3 ml/（kg?h），>24 h，或无尿>12 h

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