To investigate the clinical application of a disposable intramedullary infusion device.

Of 172 critically ill patients who admitted in the Emergency Department of Shanxi Medical University Second Hospital from January 2016 to October 2016, 90 patients from January to May, 2016 were included in control group. In these patients, after successfullybone marrow puncture, they were connected to the transfusion device and repeatedly injected drugs. Another 82 critically ill patients from June to October, 2016, who were connected with disposable marrow cavity infusion device and repeatedly injected drugs after bone marrow puncture were defined as observation group. The differences of the incidence of delayed administration, needle displacement, prolapse, limb swelling, and fluid extravasation were compared between two groups.

The incidence of delayed drug administration, translocation, limb swelling, drug exudation in the observation group were significantly lower than that in the control group, respectively (1.2% vs 11.1%, χ²=7.013, P=0.008; 1.2% vs 7.8%, χ²=4.161, P=0.041; 0 vs 5.6%, χ²=4.692, P=0.030; 3.7% vs 14.4%, χ²=5.916, P=0.015; 2.4% vs 15.6%, χ²=8.749, P=0.003).

Disposable intramedullary infusion connection device can ensure the tightness and stability of intramedullary infusion pipeline, prevent needle migration, prolapse and extravasation, and improve the safety and effectiveness of medication.