COVID-19 is the pneumonia caused by infection with a new type of coronavirus. The main clinical manifestations are fever, cough, shortness of breath, and dyspnea. Most of the symptoms can be relieved after treatment such as active antiviral measures. A few severe patients may have poor results and acute fibrinious and organizing pneumonia (AFOP) as a potential complication which should be noticed in these patients. AFOP is a rare pathological type of idiopathic interstitial pneumonia which can be idiopathic or secondary. Hormonal anti-inflammatory or immunosuppressive treatment is effective strategies. Early identification of new coronary pneumonia combined with AFOP is crucial for better outcome. Here we report a 34-year-old woman who was admitted to the hospital with a definite diagnosis of new coronary pneumonia. The patient development to a severe condition with a unresponsiveness to the treatment. Combine with the clinical and imaging results, the possibility of AFOP was considered and treated with glucocorticoids therapy. Clinical manifestations and imaging improved significantly after the treatment which indicate that the patient may complicate with the AFOP.