Dysglycemia is one of the most common metabolic disturbances in the acute phase of critically ill patients. The initiation of nutritional therapy may further promote the fluctuation of blood glucose. Hyperglycemia, hypoglycemia and glucose variability are independent risk factors for increased mortality among critically ill patients. Glycated hemoglobin, coefficient of glucose variation, time to targeting blood glucose range are useful measurements for evaluating the quality of glucose control. For different groups of critically ill patients, stratified optimization of glucose control goals, combined with computerized technology to formulate individualized glucose management, and selection of appropriate feeding methods, will benefit glucose control and improve clinical outcomes. This paper expounds the progress in blood glucose targets and control evaluation indicators, blood glucose monitoring technology and management scheme, and influence of enteral nutrition feeding mode on blood glucose in recent years.