Abstract:

This case report describes a patient with pulmonary infection caused by multidrug-resistant Acinetobacter baumannii. The patient was initially treated with a combination of Biapenem and Moxifloxacin at a local hospital, but there was no significant improvement in their condition, and they continued to experience fever symptoms. After transfer to our department, the patient was treated with Cefoperazone-Sulbactam in combination with Tigecycline. The patient's body temperature returned to normal, but they developed severe adverse reactions attributed to Tigecycline, including thrombocytopenia, coagulation abnormalities, and bleeding symptoms. Tigecycline was discontinued, and the patient was switched to treatment with Eravacycline, which resulted in a gradual recovery of platelet count and improvement in coagulation function. Eventually, the patient recovered and was discharged.

Key words: Severe pneumonia, Eravacycline, Adverse reactions, Tigecycline