Severe brain injury: pathophysiology and treatment

doi:10.3877/cma.j.jssn.2096-1537.2015.01.012

Abstract

Abstract:

Intracranial hypertension, impaired cerebral vascular auto-regulation and disrupted brain blood barrier are the three major pathophysiological characteristics in patients with severe brain injury. In accordance with these characteristics, strategies have been carried out either to control the intracranial pressure and cerebral perfusion pressure, or to regulate cerebral capillary hydrostatic pressure and oncotic pressure. The differentiation of patients with different pathophysiology and during different time windows is important factor related to clinical outcome. And this warrants further investigation.

Key words: Brain injury, Critical care medicine, Treatment, Pathophysiology

Jianxin Zhou. Severe brain injury: pathophysiology and treatment[J]. Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition), 2015, 01(01): 48-52.

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URL: https://icu.cma-cmc.com.cn/EN/10.3877/cma.j.jssn.2096-1537.2015.01.012

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