An observational study of pressure regulated volume control ventilation mode in cardio-pulmonary resuscitated patients

doi:10.3877/cma.j/jssn.2096-1537.2017.01.012

Abstract

Abstract:

Objective

To observe the effects of pressure regulated volume control (PRVC) ventilation mode in cardio-pulmonary resuscitated patients.

Methods

Thirty-five adult patients who suffered from cardiorespiratory arrest were PRVC ventilated and so called PRVC-group. An retrospective collection of another 70 adult patients who suffered from cardiorespiratory arrest were divided into two groups according to the ventilation mode the received: PCV (pressure controlled ventilation) -group (n=35) and VCV (volume control ventilation)-group (n=35). The arterial partial pressure of oxygen (PaO₂), arterial carbon dioxide partial pressure (PaCO₂), oxygenation index (OI), heart rate (HR), mean arterial pressure (MAP), central venous pressure (CVP) and peak inspimtory pressure (PIP) of the patients after successful resuscitation of spontaneous circulation (ROSC) in each group were analyzed by One-Way AVOVA. The index would be further analyzed using Student-Newman-Keuls (SNK) if statistically significant. The ROSC rates in the three groups were analyzed by chi-square test.

Results

(1)The ROSC rate in PRVC-group is higher than in PCV-group or VCV-group, with statistical significance (χ²=6.533, P<0.05). (2)The PaO₂ and OI in PRVC-group is higher than those in PCV-group and in VCV-group (F=19.601, 31.562, P<0.05), while the CVP and PIP in PRVC-group is lower than those in PCV-group and in VCV-group (F=12.045, 8.340, P<0.05), and PaCO₂, HR and MAP among these three groups have no statistically significant difference.

Conclusions

PRVC ventilation may help with a higher successful ROSC rate in cardio-pulmonary resuscitated patients due to its good ventilation support. Moreover, it can preferably improve oxygenation with little influence on hemodynamics, which also facilitate the success rate of cardio-pulmonary resuscitation.

Key words: Cardio-pulmonary resuscitation, Mechanical ventilation, Pressure regulated volume control ventilation

Zaishou Zhuang, Yan Liang, Shengdong Xue, Chun Fang, Youjun Li. An observational study of pressure regulated volume control ventilation mode in cardio-pulmonary resuscitated patients[J]. Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition), 2017, 03(01): 55-59.

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References 14

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分组	例数	性别（男/女）	年龄（岁，±s）	心脏骤停原因（例数）			CPR （min，±s）	GCS （±s）	SBP （mmHg，±s）	DBP （mmHg，±s）	HR （次/min分，±s）
				急性心肌梗死	恶性心律失常	急性左心衰竭
PRVC组	35	20/15	53.24±12.18	12	13	10	7.98±2.32	14.44±1.28	117.96±22.34	83.42±17.68	99.07±19.68
PCV组	35	23/12	57.69±11.78	14	10	11	7.64±2.08	14.06±1.56	127.66±24.82	74.50±14.78	90.56±23.22
VCV组	35	25/10	58.12±10.83	15	12	8	7.24±2.15	14.34±1.15	124.82±19.83	78.06±15.81	89.67±20.10
统计值		χ²=1.586	F=1.897	χ²=1.224			F=1.012	F=0.758	F=1.734	F=2.710	F=2.128
P值		0.453	0.156	0.874			0.370	0.473	0.182	0.071	0.125

分组	例数	性别（男/女）	年龄（岁，±s）	心脏骤停原因（例数）			CPR （min，±s）	GCS （±s）	SBP （mmHg，±s）	DBP （mmHg，±s）	HR （次/min分，±s）
				急性心肌梗死	恶性心律失常	急性左心衰竭
PRVC组	35	20/15	53.24±12.18	12	13	10	7.98±2.32	14.44±1.28	117.96±22.34	83.42±17.68	99.07±19.68
PCV组	35	23/12	57.69±11.78	14	10	11	7.64±2.08	14.06±1.56	127.66±24.82	74.50±14.78	90.56±23.22
VCV组	35	25/10	58.12±10.83	15	12	8	7.24±2.15	14.34±1.15	124.82±19.83	78.06±15.81	89.67±20.10
统计值		χ²=1.586	F=1.897	χ²=1.224			F=1.012	F=0.758	F=1.734	F=2.710	F=2.128
P值		0.453	0.156	0.874			0.370	0.473	0.182	0.071	0.125

分组	例数	ROSE成功	ROSE未成功
PRVC组	35	74.28%（26）	25.71%（9）
PCV组	35	51.43%（18）	48.57%（17）
VCV组	35	45.71%（16）	54.29%（19）
χ²值	6.533
P值	0.038

分组	例数	ROSE成功	ROSE未成功
PRVC组	35	74.28%（26）	25.71%（9）
PCV组	35	51.43%（18）	48.57%（17）
VCV组	35	45.71%（16）	54.29%（19）
χ²值	6.533
P值	0.038

分组	例数	PaO₂ （mmHg）	PaCO₂（mmHg）	CVP （mmHg）	PIP （cmH₂O）	MAP （mmHg）	HR （次/min）	OI （mmHg）
PRVC组	26	102.35±11.35^a	43.62±3.65	9.35±1.72^a	20.35±2.59^a	74.96±6.59	96.31±9.65	223.37±39.00^a
PCV组	18	86.15±9.14	46.59±4.68	11.22±1.48	22.39±2.15	74.56±7.91	100.56±10.81	167.52±11.94
VCV组	16	86.09±8.18	44.78±5.29	11.38±1.20	23.25±2.27	71.63±8.70	102.56±9.93	166.28±11.32
F值		19.601	2.384	12.045	8.340	1.038	2.122	31.562
P值		0.000	0.101	0.000	0.001	0.361	0.129	0.000

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