| 1 |
Shu H, Liu K, He Q, et al. Ulinastatin, a protease inhibitor, may inhibit allogeneic blood transfusion-associated pro-inflammatory cytokines and systemic inflammatory response syndrome and improve postoperative recovery [J]. Blood Transfus, 2014, 12(Suppl 1): S109-S118.
|
| 2 |
Sapan HB, Paturusi I, Jusuf I, et al. Pattern of cytokine (IL-6 and IL-10) level as inflammation and anti-inflammation mediator of multiple organ dysfunction syndrome (MODS) in polytrauma [J]. Int J Burns Trauma, 2016, 6(2): 37-43.
|
| 3 |
Yang R, Tenhunen J, Tonnessen TI. HMGB1 and histones play a significant role in inducing systemic inflammation and multiple organ dysfunctions in severe acute pancreatitis [J]. Int J Inflam, 2017, 2017(18): 175-177.
|
| 4 |
Zhang L, Wang CC. Inflammatory response of macrophages in infection [J]. Hepatobiliary Pancreat Dis Int, 2014, 13(2): 138-152.
|
| 5 |
Hatakeyama N, Matsuda N. Alert cell strategy: mechanisms of inflammatory response and organ protection [J]. Curr Pharm Des, 2014, 20(36): 5766-5778.
|
| 6 |
Moggia E, Koti R, Belgaumkar AP, et al. Pharmacological interventions for acute pancreatitis [J]. Cochrane Database Syst Rev, 2017, 4(1): 138-144.
|
| 7 |
Sung YH, Shin MS, Ko IG, et al. Ulinastatin suppresses lipopolysaccharide-induced prostaglandin E2 synthesis and nitric oxide production through the downregulation of nuclear factorkappaB in BV2 mouse microglial cells [J]. Int J Mol Med, 2013, 31(5): 1030-1036.
|
| 8 |
Li D, Ji H, Zhao B, et al. Therapeutic effect of ulinastatin on pulmonary fibrosis via downregulation of TGF beta1, TNF alpha and NF kappaB [J]. Mol Med Rep, 2018, 17(1): 1717-1723.
|
| 9 |
Wei F, Liu S, Luo L, et al. Anti-inflammatory mechanism of ulinastatin: Inhibiting the hyperpermeability of vascular endothelial cells induced by TNF-alpha via the RhoA/ROCK signal pathway [J]. Int Immunopharmacol, 2017, 46(2): 20-27.
|
| 10 |
Chen J, Wang J, Su C, et al. Urinary trypsin inhibitor attenuates LPS-induced endothelial barrier dysfunction by upregulation of vascular endothelial-cadherin expression [J]. Inflamm Res, 2016, 65(3): 213-224.
|
| 11 |
Craciun EM, Altfelder F, Kuss N, et al. Anti-inflammatory effects of selected drugs on activated neonatal and adult neutrophils [J]. Scand J Clin Lab Invest, 2013, 73(5): 407-413.
|
| 12 |
Atal SS, Atal S. Ulinastatin-a newer potential therapeutic option for multiple organ dysfunction syndrome [J]. J Basic Clin Physiol Pharmacol, 2016, 27(2): 91-99.
|
| 13 |
Butterfield DA, Boyd-Kimball D. Oxidative stress, amyloid-beta peptide, and altered key molecular pathways in the pathogenesis and progression of Alzheimer′s disease [J]. J Alzheimers Dis, 2018, 62(3): 1345-1367.
|
| 14 |
Zou YL, Luo WB, Xie L, et al. Targeting human 8-oxoguanine DNA glycosylase to mitochondria protects cells from high glucose-induced apoptosis [J]. Endocrine, 2018, 60(3): 445-457.
|
| 15 |
Li C, Ma D, Chen M, et al. Ulinastatin attenuates LPS-induced human endothelial cells oxidative damage through suppressing JNK/c-Jun signaling pathway [J]. Biochem Biophys Res Commun, 2016, 474(3): 572-578.
|
| 16 |
Liu B, Huang W, Xiao X, et al. Neuroprotective effect of ulinastatin on spinal cord ischemia-reperfusion injury in rabbits [J]. Oxid Med Cell Longev, 2015, 2015(6): 24-29.
|
| 17 |
Tay NQ, Lee DCP, Chua YL, et al. CD40L expression allows CD8＋T cells to promote their own expansion and differentiation through dendritic cells [J]. Front Immunol, 2017, 8(1): 48-54.
|
| 18 |
Venet F, Rimmele T, Monneret G. Management of sepsis-induced immunosuppression [J]. Crit Care Clin, 2018, 34(1): 97-106.
|
| 19 |
Zhang L, Wang N, Zhou S, et al. Preventive effect of ulinastatin on postoperative complications, immunosuppression, and recurrence in esophagectomy patients [J]. World J Surg Oncol, 2013, 11(8): 84-89.
|
| 20 |
Gao C, Li R, Wang S. Ulinastatin protects pulmonary tissues from lipopolysaccharide-induced injury as an immunomodulator [J]. J Trauma Acute Care Surg, 2012, 72(1): 169-176.
|
| 21 |
Xue L, Borne Y, Mattisson IY, et al. FADD, Caspase-3, and Caspase-8 and incidence of coronary Events [J]. Arterioscler Thromb Vasc Biol, 2017, 37(5): 983-989.
|
| 22 |
Dou C, Han M, Zhang B, et al. Chrysotoxene induces apoptosis of human hepatoblastoma HepG2 cells in vitro and in vivo via activation of the mitochondria-mediated apoptotic signaling pathway [J]. Oncol Lett, 2018, 15(4): 4611-4618.
|
| 23 |
Wang W, Liu X, Guo X, et al. Mitofusin-2 triggers cervical carcinoma cell hela apoptosis via mitochondrial pathway in mouse model [J]. Cell Physiol Biochem, 2018, 46(1): 69-81.
|
| 24 |
Anania VG, Yu K, Gnad F, et al. Uncovering a dual regulatory role for caspases during endoplasmic reticulum stress-induced cell death [J]. Mol Cell Proteomics, 2016, 15(7): 2293-2307.
|
| 25 |
Li L, Du Y, Ju F, et al. Calcium plays a key role in paraoxon-induced apoptosis in EL4 cells by regulating both endoplasmic reticulum-and mitochondria-associated pathways [J]. Toxicol Mech Methods, 2016, 26(3): 211-220.
|
| 26 |
Abraham P, Rodriques J, Moulick N, et al. Efficacy and safety of intravenous ulinastatin versus placebo along with standard supportive care in subjects with mild or severe acute pancreatitis [J]. J Assoc Physicians India, 2013, 61(8): 535-538.
|
| 27 |
Li L, Hao J, Jiang X, et al. Cardioprotective effects of ulinastatin against isoproterenol-induced chronic heart failure through the PI3KAkt, p38 MAPK and NF-kappaB pathways [J]. Mol Med Rep, 2018, 17(1): 1354-1360.
|
| 28 |
Yu Z, Rayile A, Zhang X, et al. Ulinastatin protects against lipopolysaccharide-induced cardiac microvascular endothelial cell dysfunction via downregulation of lncRNA MALAT1 and EZH2 in sepsis [J]. Int J Mol Med, 2017, 39(5): 1269-1276.
|
| 29 |
Yuhara H, Ogawa M, Kawaguchi Y, et al. Pharmacologic prophylaxis of post-endoscopic retrograde cholangiopancreatography pancreatitis: protease inhibitors and NSAIDs in a meta-analysis [J]. J Gastroenterol, 2014, 49(3): 388-399.
|
| 30 |
Caironi P, Tognoni G, Masson S, et al. Albumin replacement in patients with severe sepsis or septic shock [J]. N Engl J Med, 2014, 370(15): 1412-1421.
|