Research progress of spontaneous hyperventilation in patients with severe traumatic brain injury

doi:10.3877/cma.j.issn.2096-1537.2021.03.014

Abstract

Abstract:

Secondary brain injury prevention is critical for the severe traumatic brain injury treatment. Induced hyperventilation can decrease intracranial pressure by reducing cerebral blood volume; however, it is not recommended as routine therapy in severe traumatic brain injury since the decreased cerebral blood flow which may aggravate brain ischemia. Meanwhile, a high prevalence of spontaneous hyperventilation in patients with an acute brain injury, which is characterized as certain degrees of hypocapnia, has attracted more attention in recent years due to closely related to the long-term adverse outcome. We has reviewed the epidemiology, pathophysiology mechanisms, clinical prognosis, and prevention methods of spontaneous hyperventilation in severe traumatic brain injury, aiming to improve the critical care physicians' awareness and facilitate fundamental and clinical research.

Key words: Severe traumatic brain injury, Secondary brain injury, Spontaneous hyperventilation, Hypocapnia, Cerebral blood flow

Ning Zhu, Rui Su, Jianxin Zhou, Hongliang Li. Research progress of spontaneous hyperventilation in patients with severe traumatic brain injury[J]. Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition), 2021, 07(03): 272-276.

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https://icu.cma-cmc.com.cn/EN/Y2021/V07/I03/272

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