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Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition) ›› 2021, Vol. 07 ›› Issue (03): 268-271. doi: 10.3877/cma.j.issn.2096-1537.2021.03.013

• Review • Previous Articles     Next Articles

Research update on the regulatory effects of alveolar macrophage autophagy on lung injury in acute respiratory distress syndrome

Xuecheng Dong1, Ling Liu1,()   

  1. 1. Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing 210009, China
  • Received:2021-04-13 Online:2021-08-28 Published:2021-10-20
  • Contact: Ling Liu

Abstract:

Uncontrolled inflammation is the fundament of the pathogenesis of acute respiratory distress syndrome (ARDS) and most researches show that autophagy of alveolar macrophages plays an important regulatory role in the inflammation of ARDS. This review focuses on the mechanism of alveolar macrophage autophagy in ARDS,states the influence of alveolar macrophage autophagy in lung injury, and provides research directions in the treatment of ARDS.

Key words: Acute respiratory distress syndrome, Alveolar macrophages, Autophagy

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