Advances in photobiomodulation as adjunctive therapy in severe pulmonary infections

doi:10.3877/cma.j.issn.2096-1537.2022.02.014

Abstract

Abstract:

Pulmonary infection is one of the commonest infectious diseases in clinical practice. Its incidence and mortality rates increase year by year. Severe pneumonia, especially COVID-19, places a significant burden on societies and families. There is, therefore, an urgent need to develop more effective antimicrobial and anti-inflammatory strategies to control severe pulmonary infections. PBM, with intracellular photochemical reactions affecting cellular metabolic pathways and gene expression patterns, is a novel therapeutic tool in medicine. It has antibacterial and bactericidal effects, eliminate inflammation, regulate immunity, and promote blood circulation and tissue repair. This review focuses on the cellular and molecular mechanisms of PBM to explore the feasibility of PBM as adjuvant therapy for pulmonary infection and find new treatment strategies for patients with severe pneumonia and improve their prognosis.

Key words: Photobiomodulation, Severe pneumonia, Low-level laser therapy

Qingqing Guo, Jiandong Lin. Advances in photobiomodulation as adjunctive therapy in severe pulmonary infections[J]. Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition), 2022, 08(02): 173-179.

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