Progress in fluid resuscitation strategy in septic patients

doi:10.3877/cma.j.issn.2096-1537.2024.02.014

Abstract

Abstract:

Sepsis is a major global health problem with a high mortality. Fluid resuscitation is an important part of early emergency treatment of sepsis, and timely and effective fluid resuscitation can significantly reduce mortality. In recent years, with further understanding sepsis and continuous increase of evidence-based evidence, fluid resuscitation treatment have also been updated. This article reviews advances in fluid resuscitation strategies for sepsis with a view to update understanding of fluid resuscitation in sepsis.

Key words: Sepsis, Septic shock, Fluid resuscitation

Mingmin Pang, Meichen Yan, Guangfeng Liu, Jibin Gong, Nana Xu, Yue Zheng, Shaohua Fan, Hao Wang. Progress in fluid resuscitation strategy in septic patients[J]. Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition), 2024, 10(02): 189-195.

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References 67

14	ARISE Investigators, ANZICS Clinical Trials Group, Peake SL, et al. Goal-directed resuscitation for patients with early septic shock [J]. N Engl J Med, 2014, 371(16): 1496-1506.
15	Mouncey PR, Osborn TM, Power GS, et al. Protocolised Management In Sepsis (ProMISe): a multicentre randomised controlled trial of the clinical effectiveness and cost-effectiveness of early, goal-directed, protocolised resuscitation for emerging septic shock [J]. Health Technol Assess Winch Engl, 2015, 19(97): i-xxv, 1-150.
16	Rhodes A, Evans LE, Alhazzani W, et al. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 [J]. Intensive Care Med, 2017, 43(3): 304-377.
17	Koh IHJ, Menchaca-Diaz JL, Koh TH, et al. Microcirculatory evaluation in sepsis: a difficult task [J]. Shock Augusta Ga, 2010, 34 Suppl 1: 27-33.
18	Kraut JA, Madias NE. Lactic acidosis [J]. N Engl J Med, 2014, 371(24): 2309-2319.
19	MacLean LD, Mulligan WG, McLean AP, et al. Patterns of septic shock in man--a detailed study of 56 patients [J]. Ann Surg. 1967, 166(4): 543-562.
20	Vincent JL, Mongkolpun W. Current management of Gram-negative septic shock [J]. Curr Opin Infect Dis, 2018, 31(6): 600-605.
21	Acheampong A, Vincent JL. A positive fluid balance is an independent prognostic factor in patients with sepsis [J]. Crit Care Lond Engl, 2015, 19(1): 251.
22	Marik PE, Linde-Zwirble WT, Bittner EA, et al. Fluid administration in severe sepsis and septic shock, patterns and outcomes: an analysis of a large national database [J]. Intensive Care Med, 2017, 43(5): 625-632.
23	Hjortrup PB, Haase N, Bundgaard H, et al. Restricting volumes of resuscitation fluid in adults with septic shock after initial management: the CLASSIC randomised, parallel-group, multicentre feasibility trial [J]. Intensive Care Med, 2016, 42(11): 1695-1705.
24	Cordemans C, De Laet I, Van Regenmortel N, et al. Aiming for a negative fluid balance in patients with acute lung injury and increased intra-abdominal pressure: a pilot study looking at the effects of PAL-treatment [J]. Ann Intensive Care, 2012, 2 Suppl 1: S15.
25	Vincent JL, De Backer D. Circulatory shock [J]. N Engl J Med, 2013, 369(18): 1726-1734.
26	Casey JD, Brown RM, Semler MW. Resuscitation fluids [J]. Curr Opin Crit Care, 2018, 24(6): 512-518.
27	任建安. 外科感染性疾病的血液滤过治疗 [J]. 中国实用外科杂志, 2008, 28(6): 429-430.
28	Evans L, Rhodes A, Alhazzani W, et al. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021 [J]. Intensive Care Med, 2021, 47(11): 1181-1247.
29	Bentzer P, Griesdale DE, Boyd J, et al. Will this hemodynamically unstable patient respond to a bolus of intravenous fluids? [J]. JAMA, 2016, 316(12): 1298-1309.
30	Cherpanath TGV, Geerts BF, Lagrand WK, et al. Basic concepts of fluid responsiveness [J]. Neth Heart J Mon J Neth Soc Cardiol Neth Heart Found, 2013, 21(12): 530-536.
31	Marik PE, Cavallazzi R. Does the central venous pressure predict fluid responsiveness? An updated meta-analysis and a plea for some common sense [J]. Crit Care Med, 2013, 41(7): 1774-1781.
32	Shah MR, Hasselblad V, Stevenson LW, et al. Impact of the pulmonary artery catheter in critically ill patients: meta-analysis of randomized clinical trials [J]. JAMA, 2005, 294(13): 1664-1670.
33	Hanson J, Lam SWK, Alam S, et al. The reliability of the physical examination to guide fluid therapy in adults with severe falciparum malaria: an observational study [J]. Malar J, 2013, 12: 348.
34	Saugel B, Kirsche SV, Hapfelmeier A, et al. Prediction of fluid responsiveness in patients admitted to the medical intensive care unit [J]. J Crit Care, 2013, 28(4): 537.e1-9.
35	Fessler HE, Brower RG, Wise RA, et al. Mechanism of reduced LV afterload by systolic and diastolic positive pleural pressure [J]. J Appl Physiol (1985), 1988, 65(3): 1244-1250.
36	Monnet X, Marik PE, Teboul JL. Prediction of fluid responsiveness: an update [J]. Ann Intensive Care, 2016, 6(1): 111.
37	Monnet X, Teboul JL. Passive leg raising [J]. Intensive Care Med, 2008, 34(4): 659-663.
38	Borthwick HA, Brunt LK, Mitchem KL, et al. Does lactate measurement performed on admission predict clinical outcome on the intensive care unit? A concise systematic review [J]. Ann Clin Biochem, 2012, 49(Pt 4): 391-394.
39	Karon BS, Tolan NV, Wockenfus AM, et al. Evaluation of lactate, white blood cell count, neutrophil count, procalcitonin and immature granulocyte count as biomarkers for sepsis in emergency department patients [J]. Clin Biochem, 2017, 50(16-17): 956-958.
40	张井晓, 尹梅, 陈晓梅, 等. 早期乳酸面积对老年脓毒性休克患者预后评估的价值[J]. 中华医学杂志, 2016, 96(33): 2640-2643.
41	Wang H, Li Z, Yin M, et al. Combination of acute physiology and chronic health evaluation Ⅱ score, early lactate area, and N-terminal prohormone of brain natriuretic peptide levels as a predictor of mortality in geriatric patients with septic shock [J]. J Crit Care, 2015, 30(2): 304-309.
42	Ait-Oufella H, Bige N, Boelle PY, et al. Capillary refill time exploration during septic shock [J]. Intensive Care Med, 2014, 40(7): 958-964.
43	Vignon P, Repessé X, Bégot E, et al. Comparison of echocardiographic indices used to predict fluid responsiveness in ventilated patients [J]. Am J Respir Crit Care Med, 2017, 195(8): 1022-1032.
44	Corl KA, Azab N, Nayeemuddin M, et al. Performance of a 25% inferior vena cava collapsibility in detecting fluid responsiveness when assessed by novice versus expert physician sonologists [J]. J Intensive Care Med, 2020, 35(12): 1520-1528.
45	Orso D, Paoli I, Piani T, et al. Accuracy of ultrasonographic measurements of inferior vena cava to determine fluid responsiveness: a systematic review and meta-analysis [J]. J Intensive Care Med, 2020, 35(4): 354-363.
46	王小亭, 刘大为, 于凯江, 等. 中国重症超声专家共识 [J]. 中华内科杂志, 2016, 55(11): 900-912.
47	张磊云, 李少洪, 姚一鸣, 等. 床旁超声指导下早期液体复苏治疗重症脓毒症的临床效果 [J]. 智慧健康, 2022, 8(31): 25-28, 32.
48	张功伟, 王伟, 张诗渊, 等. 床旁超声与脉搏指示连续心排血量监测在脓毒症休克患者早期液体复苏治疗中的疗效比较 [J]. 中国现代医学杂志, 2022, 32(20): 8-13.
49	Awad S, Allison SP, Lobo DN. The history of 0.9% saline [J]. Clin Nutr Edinb Scotl, 2008, 27(2): 179-188.
50	Yunos NM, Bellomo R, Glassford N, et al. Chloride-liberal vs. chloride-restrictive intravenous fluid administration and acute kidney injury: an extended analysis [J]. Intensive Care Med, 2015, 41(2): 257-264.
51	Krajewski ML, Raghunathan K, Paluszkiewicz SM, et al. Meta-analysis of high- versus low-chloride content in perioperative and critical care fluid resuscitation [J]. Br J Surg, 2015, 102(1): 24-36.
1	Ladzinski AT, Thind GS, Siuba MT. Rational fluid resuscitation in sepsis for the hospitalist: a narrative review [J]. Mayo Clin Proc, 2021, 96(9): 2464-2473.
2	Foëx BA. How the cholera epidemic of 1831 resulted in a new technique for fluid resuscitation [J]. Emerg Med J EMJ, 2003, 20(4): 316-318.
3	Hammond DA, Lam SW, Rech MA, et al. Balanced crystalloids versus saline in critically ill adults: a systematic review and meta-analysis [J]. Ann Pharmacother, 2020, 54(1): 5-13.
4	Rivers E, Nguyen B, Havstad S, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock [J]. N Engl J Med, 2001, 345(19): 1368-1377.
5	Levy MM, Dellinger RP, Townsend SR, et al. The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis [J]. Intensive Care Med, 2010, 36(2): 222-231.
6	Evans L, Rhodes A, Alhazzani W, et al. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021 [J]. Intensive Care Med, 2021, 47(11): 1181-1247.
7	Dellinger RP, Levy MM, Rhodes A, et al. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012 [J]. Intensive Care Med, 2013, 39(2): 165-228.
8	Levy MM, Evans LE, Rhodes A. The Surviving Sepsis Campaign Bundle: 2018 update [J]. Intensive Care Med, 2018, 44(6): 925-928.
9	吴飞, 陈含冰, 陈齐红, 等. 初始30 mL/kg液体复苏完成时间对脓毒性休克患者预后的影响 [J]. 中华危重病急救医学, 2021, 33(7): 803-808.
10	Owens TM, Watson WC, Prough DS, et al. Limiting initial resuscitation of uncontrolled hemorrhage reduces internal bleeding and subsequent volume requirements [J]. J Trauma, 1995, 39(2): 200-207, discussion 208-209.
11	Kelm DJ, Perrin JT, Cartin-Ceba R, et al. Fluid overload in patients with severe sepsis and septic shock treated with early goal-directed therapy is associated with increased acute need for fluid-related medical interventions and hospital death [J]. Shock Augusta Ga, 2015, 43(1): 68-73.
12	Jozwiak M, Hamzaoui O, Monnet X, et al. Fluid resuscitation during early sepsis: a need for individualization [J]. Minerva Anestesiol, 2018, 84(8): 987-992.
13	Lilly CM. Protocol-based care for early septic shock [J]. N Engl J Med, 2014, 371(4): 386-387.
52	Yunos NM, Bellomo R, Hegarty C, et al. Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults [J]. JAMA, 2012, 308(15): 1566-1572.
53	Zampieri FG, Machado FR, Biondi RS, et al. Effect of intravenous fluid treatment with a balanced solution vs 0.9% saline solution on mortality in critically ill patients: the BaSICS randomized clinical trial [J]. JAMA, 2021, 326(9): 1-12.
54	孙习鹏, 陆瑶华, 李星霞, 等. 人血白蛋白与晶体液对成人脓毒症及脓毒症休克患者液体复苏作用Meta分析 [J]. 医药导报, 2017, 36(7): 804-808.
55	He H, Liu D, Ince C. Colloids and the Microcirculation [J]. Anesth Analg, 2018, 126(5): 1747-1754.
56	Finfer S, Bellomo R, Boyce N, et al. A comparison of albumin and saline for fluid resuscitation in the intensive care unit [J]. N Engl J Med, 2004, 350(22): 2247-2256.
57	Caironi P, Tognoni G, Masson S, et al. Albumin replacement in patients with severe sepsis or septic shock [J]. N Engl J Med, 2014, 370(15): 1412-1421.
58	Park CHL, de Almeida JP, de Oliveira GQ, et al. Lactated ringer's versus 4% albumin on lactated Ringer's in early sepsis therapy in cancer patients: a pilot single-center randomized trial [J]. Crit Care Med, 2019, 47(10): e798-e805.
59	Myburgh JA, Finfer S, Bellomo R, et al. Hydroxyethyl starch or saline for fluid resuscitation in intensive care [J]. N Engl J Med, 2012, 367(20): 1901-1911.
60	Perner A, Haase N, Guttormsen AB, et al. Hydroxyethyl starch 130/0.42 versus Ringer's acetate in severe sepsis [J]. N Engl J Med, 2012, 367(2): 124-134.
61	Haase N, Perner A, Hennings LI, et al. Hydroxyethyl starch 130/0.38-0.45 versus crystalloid or albumin in patients with sepsis: systematic review with meta-analysis and trial sequential analysis [J]. BMJ, 2013, 346: f839.
62	Rochwerg B, Alhazzani W, Sindi A, et al. Fluid resuscitation in sepsis: a systematic review and network meta-analysis [J]. Ann Intern Med, 2014, 161(5): 347-355.
63	Annane D, Siami S, Jaber S, et al. Effects of fluid resuscitation with colloids vs crystalloids on mortality in critically ill patients presenting with hypovolemic shock: the CRISTAL randomized trial [J]. JAMA, 2013, 310(17): 1809-1817.
64	殷晓春, 王荣民, 何玉凤, 等. 人工氧载体研究进展 [J]. 化学进展, 2011, 23(5): 963-973.
65	孙绪德, 柴伟, 高昌俊, 等. 高氧液对家兔心肌缺血/再灌注细胞凋亡的影响 [J]. 中国临床康复, 2003, 7(17): 2434-2435.
66	孙绪德, 柴伟, 马加海, 等. 高氧液对家兔心肌缺血再灌注损伤生化指标和超微结构的影响 [J]. 第四军医大学学报, 2001, 22(13): 1176-1178.
67	孙绪德, 柴伟, 张贵和, 等. 高氧液在抢救重度失血性休克中的临床应用 [J]. 临床麻醉学杂志, 2003, 19(6): 346-347.

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