Interpretation of the Practice Standards for Adult Extracorporeal Membrane Oxygenation Technology（2024 Edition）：combination of ECMO and CRRT

doi:10.3877/cma.j.issn.2096-1537.2025.01.011

Abstract

Abstract:

In recent years，extracorporeal membrane oxygenation （ECMO） has been increasingly used in clinical practice as a critical advanced life support modality for critically ill patients with acute respiratory/circulatory failure. These patients often develop complications such as acute kidney injury（AKI） and volume overload，necessitating renal replacement therapy （RRT）. The indications and optimal timing for initiating continuous renal replacement therapy （CRRT） should be determined through individualized assessment based on the patient's volume status and severity of AKI-related metabolic disturbances. In ECMO patients，CRRT can be connected to ECMO in various ways，and there is currently no evidence to suggest different methods of combining ECMO and CRRT affect clinical outcomes. The combined use of ECMO and CRRT is a safe and effective technique to improve fluid balance and stabilize the internal environment. We focus on interpreting key clinical issues that addressed in thePractice Standards for Adult Extracorporeal Membrane Oxygenation Technology （2024 Edition），including indications，timing，connection methods，prognosis and risk factors associated with ECMO-CRRT combined therapy.

Key words: Extracorporeal membrane oxygenation, Continuous renal replacement therapy, Mortality

Pan Pan, Songqiao Liu. Interpretation of the Practice Standards for Adult Extracorporeal Membrane Oxygenation Technology（2024 Edition）：combination of ECMO and CRRT[J]. Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition), 2025, 11(01): 51-54.

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