Sepsis-induced coagulopathy：progress and prospects in 2024

doi:10.3877/cma.j.issn.2096-1537.2025.02.001

Abstract

Abstract:

Sepsis is often accompanied by complex coagulation dysfunction，particularly disseminated intravascular coagulation （DIC），which significantly exacerbates disease severity and increases mortality.Despite advances in therapeutic approaches in recent years，sepsis-induced coagulopathy （SIC） remains a significant clinical challenge.Recent studies have elucidated the underlying mechanisms of SIC and identified novel therapeutic targets，providing potential treatment strategies for clinical practice.We summarize the latest research progress in SIC dysfunction，analyze current treatment trends，and explore future research directions.

Key words: Sepsis, Coagulopathy, Anticoagulant therapy, Diagnostic biomarkers

Lina Zhang, Chuyu Shen, Xinyu Yang, Haibo Qiu, Ben Lyu. Sepsis-induced coagulopathy：progress and prospects in 2024[J]. Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition), 2025, 11(02): 105-111.

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URL: https://icu.cma-cmc.com.cn/EN/10.3877/cma.j.issn.2096-1537.2025.02.001

https://icu.cma-cmc.com.cn/EN/Y2025/V11/I02/105

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