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Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition) ›› 2025, Vol. 11 ›› Issue (02): 112-116. doi: 10.3877/cma.j.issn.2096-1537.2025.02.002

• Annual Progress • Previous Articles    

Neuroimmunity in sepsis-induced multiple organ dysfunction:progress and prospects in 2024

Ling Zhang1, Jianfeng Xie1,()   

  1. 1. Jiangsu Provincial Key Laboratory of Critical Care Medicine,Department of Critical Care Medicine,Zhongda Hospital,School of Medicine,Southeast University,Nanjing 210009,China
  • Received:2025-02-07 Online:2025-05-28 Published:2025-07-18
  • Contact: Jianfeng Xie

Abstract:

Sepsis poses a serious threat to human health,but due to the unclear pathogenesis of sepsis,there is currently no universally recognized effective treatment drug.Recently,a large number of studies have revealed that neuroimmune interactions play an important role in the occurrence and development of sepsis,closely related to multi-organ injury in sepsis,suggesting that neuroimmunity can provide effective therapeutic targets for improving organ function in sepsis.This article briefly describes the neuroimmune interactions and potential neuroimmune regulatory targets during organ injury in sepsis.

Key words: Sepsis, Multiple organ dysfunction, Neuroimmune interactions

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