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Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition) ›› 2017, Vol. 03 ›› Issue (03): 178-181. doi: 10.3877/cma.j.issn.2096-1537.2017.03.005

Special Issue: Critical care medicine

• Lecture • Previous Articles     Next Articles

Research progress of presepsin: a newly identified soluble CD14 subtype as a marker for sepsis

Liren Lai1,()   

  1. 1. Department of Emergency and Critical Care Medicine, the First Affiliated Hospital of Xiamen University, Xiamen 361000, China
  • Received:2016-09-23 Online:2017-08-28 Published:2017-08-28
  • Contact: Liren Lai
  • About author:
    Corresponding author: Lai Liren, Email:

Abstract:

Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection, which is the leading cause of death in critically ill patients in intensive care unit (ICU). Circulating bio-markers are helpful in early diagnosis of sepsis, evaluating the severity, guiding antimicrobials management and predicting outcomes. Unlike procalcitonin, interleukin-6 or C-reactive protein, an newly discovered bio-marker ″Presepsin″ has been shown as a useful effect on early diagnosis and accessment of sepsis, which will become to be a prospective clinical application.

Key words: Sepsis, Septic shock, sCD14-ST, Presepsin

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