Role of extracellular vesicles from lung epithelial cells and macrophages in lung inflammatory diseases

doi:10.3877/cma.j.issn.2096-1537.2020.02.021

Abstract

Abstract:

Increasing attention has been paid to the emerging role of extracellular vesicles (EVs) in lung homeostasis and pathologic conditions recently. Various cells can release EVs, and they can encapsulate different kinds of molecules, such as nucleic acids and proteins into EVs, as modulators of intercellular communications. More and more evidence demonstrates an important role for EVs in maintaining lung microenvironment homeostasis and mediating transmission of inflammatory signals between lung epithelial cells and macrophages. The purpose of this review is to discuss the role of EVs from lung epithelial cells and macrophages in lung inflammatory diseases.

Key words: Lung, Epithelial cells, Macrophages, Extracellular vesicles, Lung microenvironment homeostasis

Xu Liu, Ming Xue, Haibo Qiu. Role of extracellular vesicles from lung epithelial cells and macrophages in lung inflammatory diseases[J]. Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition), 2020, 06(02): 211-214.

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URL: https://icu.cma-cmc.com.cn/EN/10.3877/cma.j.issn.2096-1537.2020.02.021

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