Research progress of characteristics and protection of right heart function in patients with acute respiratory distress syndrome

doi:10.3877/cma.j.issn.2096-1537.2020.03.016

Abstract

Abstract:

Acute respiratory distress syndrome (ARDS) is a common refractory critical disease in the ICU, and its mortality rate is still high. Mechanical ventilation is an important treatment for ARDS. Thanks to the in-depth understanding of the pathogenesis of ARDS, scholars have paid attention to the importance of the right heart and pulmonary circulation. The anatomic and physiological characteristics of the right ventricle determine that it is very sensitive to the afterload, and improper parameters of the ventilator may aggravate pulmonary hypertension and cause acute cor pulmonale. The combination of low tidal volume and optimal positive end expiratory pressure can improve the proportion of ventilatory blood flow, improve oxygenation, reduce ventilator-related lung damage and its impact on right heart function, and avoid the transformation of natural acute cor pulmonale into iatrogenic acute cor pulmonale. Monitoring right heart function should be a key point in the management of critical ARDS patients. This paper discusses the characteristics, protection, and treatment of right heart function in ARDS patients in order to improve the clinical understanding and treatment level for this condition.

Key words: Acute respiratory distress syndrome, Acute cor pulmonale, Pulmonary hypertension, Right ventricular function

Zidan Wang, Xiu Li, Xue Li, Junfang Li, Rong Li, Jianfang Liu, Liang Shan. Research progress of characteristics and protection of right heart function in patients with acute respiratory distress syndrome[J]. Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition), 2020, 06(03): 322-328.

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