Value of pulse-indicator continuous cardiac output monitoring in management guiding of septic shock: a Meta-analysis

doi:10.3877/cma.j.issn.2096-1537.2021.01.008

Abstract

Abstract:

Objective

To investigate the value of pulse-indicator continuous cardiac output (PiCCO) in guiding management of septic shock.

Methods

The PubMed, CNKI, WangFang Databases were searched for the short term outcomes of PiCCO guided management in septic shock patients, compared with central venous pressure (CVP) guided outcomes from January 2011 to March 2020. Two reviewers independently screened the literatures based on the inclusion and exclusion criteria. Data were analyzed by Rev Man 5.3 software.

Results

Twenty one studies involving 1572 patients were included. Compared with CVP group, patients in PiCCO group had reduced 28 day mortality (OR=0.55, 95%CI: 0.43-0.70, P＜0.001) and shortened duration of mechanical ventilation (SD=-1.77, 95%CI: -2.36 - -1.19, P＜0.001).

Conclusion

In septic shock patients, managements guided by PiCCO has an advantage over conventional CVP with decreased 28 day mortality and shortened duration of mechanical ventilation.

Key words: Septic shock, Pulse-indicator continuous cardiac output, Central venous pressure

Xuezhong Xing, Yong Gao, Haijun Wang, Shining Qu, Chulin Huang, Hao Zhang. Value of pulse-indicator continuous cardiac output monitoring in management guiding of septic shock: a Meta-analysis[J]. Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition), 2021, 07(01): 43-47.

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References 37

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纳入研究	例数（P/C）	年龄（岁）（P/C）	脓毒症休克定义	严重程度评分或APACHE Ⅱ评分（P/C）	结局指标
Zhang等^[11]	129/145	-/-	2003年国际定义^[8]	-/-	①
李文杰^[12]	9/9	-/-	-	-/-	①
唐坎凯等^[13]	32/31	56.5±7.6/53.5±6.8	2003年国际定义^[8]	21.5±4.6/20.4±3.7	①②
伍义等^[14]	21/20	-/-	-	-/-	①②
吴伟东等^[15]	20/20	49.2±14.8/48.1±16.2	2007年中国定义^[9]	-/-	①②
张汝敏等^[16]	20/20	49±8/47±9	-	22±6/22±5	①②
卢年芳等^[17]	42/40	59.6±12.4/60.3±13.2	2007年中国定义^[9]	28.9±10.1/27.6±8.9	①②
胡健等^[18]	33/33	-/-	-	-/-	①②
刘建凌等^[19]	39/41	40.1±35.2/40.5±35.3	-	26.9±5.8/26.0±6.2	①②
刘素霞等^[20]	13/15	69.5±6.9/66.1±7.2	2014年中国定义^[10]	-/-	①②
刘振菁等^[21]	30/30	56±9.5/54±10.1	2014年中国定义^[10]	26±4.5/26±5.8^*	①②
王逸君等^[22]	20/24	-/-	2014年中国定义^[10]	-/-	①②
黄庆生等^[23]	43/43	63.5±8.2/63.9±9.0	-	20.5±4.6/20.8±4.1	①
温江华等^[24]	63/63	-/-	-	-/-	①②
陈俊峰等^[25]	45/45	65.8±7.1/62.1±6.8	-	-/-	①
周林等^[26]	63/63	56.2±5.8/53.6±5.5	2007中国定义^[9]	27.3±6.9/28.1±6.7	①②
冯丽芝等^[27]	30/30	62.3±17.3/59.3±20.9	2014年中国定义^[10]	22.3±5.5/20.4±5.2	①②
钱志贤等^[28]	30/30	68.4±13.6/70.3±14.2	2003年国际定义^[8]	25.1±6.2/26.7±6.5	①②
王金莉等^[29]	30/30	53.6±6.4/56.1±5.7	-	24.5±4.6/25.3±4.9	①②
崔晓悦等^[30]	30/30	-/-	2003年国际定义^[8]	-/-	①②
贺芙云等^[31]	34/34	64.7±7.3/65.9±7.6	-	-/-	①②

纳入研究	例数（P/C）	年龄（岁）（P/C）	脓毒症休克定义	严重程度评分或APACHE Ⅱ评分（P/C）	结局指标
Zhang等^[11]	129/145	-/-	2003年国际定义^[8]	-/-	①
李文杰^[12]	9/9	-/-	-	-/-	①
唐坎凯等^[13]	32/31	56.5±7.6/53.5±6.8	2003年国际定义^[8]	21.5±4.6/20.4±3.7	①②
伍义等^[14]	21/20	-/-	-	-/-	①②
吴伟东等^[15]	20/20	49.2±14.8/48.1±16.2	2007年中国定义^[9]	-/-	①②
张汝敏等^[16]	20/20	49±8/47±9	-	22±6/22±5	①②
卢年芳等^[17]	42/40	59.6±12.4/60.3±13.2	2007年中国定义^[9]	28.9±10.1/27.6±8.9	①②
胡健等^[18]	33/33	-/-	-	-/-	①②
刘建凌等^[19]	39/41	40.1±35.2/40.5±35.3	-	26.9±5.8/26.0±6.2	①②
刘素霞等^[20]	13/15	69.5±6.9/66.1±7.2	2014年中国定义^[10]	-/-	①②
刘振菁等^[21]	30/30	56±9.5/54±10.1	2014年中国定义^[10]	26±4.5/26±5.8^*	①②
王逸君等^[22]	20/24	-/-	2014年中国定义^[10]	-/-	①②
黄庆生等^[23]	43/43	63.5±8.2/63.9±9.0	-	20.5±4.6/20.8±4.1	①
温江华等^[24]	63/63	-/-	-	-/-	①②
陈俊峰等^[25]	45/45	65.8±7.1/62.1±6.8	-	-/-	①
周林等^[26]	63/63	56.2±5.8/53.6±5.5	2007中国定义^[9]	27.3±6.9/28.1±6.7	①②
冯丽芝等^[27]	30/30	62.3±17.3/59.3±20.9	2014年中国定义^[10]	22.3±5.5/20.4±5.2	①②
钱志贤等^[28]	30/30	68.4±13.6/70.3±14.2	2003年国际定义^[8]	25.1±6.2/26.7±6.5	①②
王金莉等^[29]	30/30	53.6±6.4/56.1±5.7	-	24.5±4.6/25.3±4.9	①②
崔晓悦等^[30]	30/30	-/-	2003年国际定义^[8]	-/-	①②
贺芙云等^[31]	34/34	64.7±7.3/65.9±7.6	-	-/-	①②

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