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Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition) ›› 2023, Vol. 09 ›› Issue (01): 40-45. doi: 10.3877/cma.j.issn.2096-1537.2023.01.008

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Application scenario of extracorporeal carbon dioxide removal technology in Intensive Care Unit

Jingen Xia1,(), Shiyu Hu1   

  1. 1. Department of Respiratory and Critical Care Medicine, China-Japan Friendship Hospital, National Center for Respiratory Medicine, Institute of Respiratory Diseases, Chinese Academy of Medical Sciences, National Clinical Medical Research Center for Respiratory Diseases, Beijing 100029, China
  • Received:2022-11-22 Online:2023-02-28 Published:2023-04-07
  • Contact: Jingen Xia

Abstract:

Extracorporeal carbon dioxide removal (ECCO2R) is an extracorporeal life support technology, designed to remove excessive carbon dioxide generated by the body through extracorporeal membrane lung ("artificial lung"), thus reducing patients' ventilatory demand and ventilator support level. With the improvement of related extracorporeal life support technologies and the accumulation of clinical experience, recent studies have suggested that ECCO2R has important potential value in a variety of clinical scenarios. However, it is still imperative but it is urgent to further standardize its clinical indications and bedside management through large sample clinical studies. This article reviewed the application value of ECCO2R in severe application scenarios, such as acute respiratory distress syndrome (ARDS), acute exacerbation of chronic obstructive pulmonary disease (AECOPD), perioperative period of lung transplantation, and persistent status of asthma, so as to provide more reference for the application of ECCO2R in severe clinical scenarios.

Key words: Extracorporeal carbon dioxide removal, Acute respiratory distress syndrome, Acute exacerbation of chronic obstructive pulmonary disease, Perioperative period of lung transplantation, Persistent status of asthma

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