Chinese Guidelines for Management of Severe Sepsis/Septic Shock: How to see early goal-directed therapy

doi:10.3877/cma.j.jssn.2096-1537.2016.01.009

Abstract

Abstract:

Severe sepsis and septic shock are important causes of mortality of critically ill patients. A decade ago, early goal-directed therapy (EGDT) was used as a novel approach to reduce the mortality, and the versions of the Surviving Sepsis Campaign have incorporated it as a recommendation. However, recent randomly controlled studies have shown that EGDT could not reduce the mortality. Thus, the clinical value of EGDT is suspected. Comprehensive analysis of the studies about EGDT showed that EGDT is useful, but the major elements of this approach appear to be flawed. Possibly a new method will effectively guide clinical treatments.

Key words: Resuscitation, Shock, Sepsis, Septic shock

Hongjie Tong, Caibao Hu, XiaoChun Lv, Guolong Cai. Chinese Guidelines for Management of Severe Sepsis/Septic Shock: How to see early goal-directed therapy[J]. Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition), 2016, 02(01): 36-39.

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URL: https://icu.cma-cmc.com.cn/EN/10.3877/cma.j.jssn.2096-1537.2016.01.009

https://icu.cma-cmc.com.cn/EN/Y2016/V02/I01/36

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