Research progress in acute respiratory distress syndrome related pulmonary fibrosis

doi:10.3877/cma.j.issn.2096-1537.2024.03.009

Abstract

Abstract:

Acute respiratory distress syndrome (ARDS) is refractory hypoxemia characterized by diffuse alveolar injury. As a complication, pulmonary fibrosis often leads to high mortality, especially in severe COVID-19. The heterogeneity of ARDS is prominent. Current researches focus on precise treatment for subtypes of ARDS. However, mechanism of fibroproliferative ARDS is complex, lack of diagnostic biomarkers for clinical application, which increases the difficulty of treatment and predicting prognosis. This article reviews research progress of pulmonary fibrosis pathogenesis in ARDS.

Key words: Acute respiratory distress syndrome, Pulmonary f ibrosis, Coronavirus disease 2019

Xue Tian, Hui Xie, Ruilan Wang. Research progress in acute respiratory distress syndrome related pulmonary fibrosis[J]. Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition), 2024, 10(03): 258-264.

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URL: https://icu.cma-cmc.com.cn/EN/10.3877/cma.j.issn.2096-1537.2024.03.009

https://icu.cma-cmc.com.cn/EN/Y2024/V10/I03/258

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