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Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition) ›› 2024, Vol. 10 ›› Issue (04): 338-343. doi: 10.3877/cma.j.issn.2096-1537.2024.04.005

• Interpretation of Guideline • Previous Articles     Next Articles

Interpretation of an update on clinical practice guideline of adult patients with acute respiratory distress syndrome of American Thoracic Society

Xiaoxia Wang1, Dan Wu2, Jiangying Zhang1, Yahan Wu1, Yingnan Hao1   

  1. 1.Department of Intensive Care Unit,Inner Mongolia Autonomous Region People’s Hospital, Hohhot 010017, China
    2.Department of Pharmacy, Inner Mongolia Autonomous Region People’s Hospital, Hohhot 010017, China
  • Received:2024-02-01 Online:2024-11-28 Published:2025-01-20

Abstract:

Acute respiratory distress syndrome (ARDS) is a type of non-cardiogenic pulmonary edema with a high mortality rate.With the pandemic of novel coronavirus infection (COVID-19), the diagnosis and treatment of ARDS have attracted renewed attention in clinical practice.Based on the updated evidence-based research, the American Thoracic Society issued guidelines for the treatment of ARDS in 2023, involving four parts: the use of corticosteroids, the selection of extracorporeal membrane oxygenation (ECMO), the application of neuromuscular blocking agents, and the use of positive end-expiratory pressure (PEEP) in ARDS patients.The guidelines recommends corticosteroids for patients with ARDS.Venovenous extracorporeal membrane oxygenation (V-V ECMO) is recommended for selected patients with severe ARDS.Neuromuscular blockers are recommended for patients with early severe ARDS.For patients with moderate-to-severe ARDS, a higher PEEP is recommended over a lower PEEP without lung recruitment maneuvers (LRMs).Prolonged lung recruitment maneuvers are not recommended for patients with moderate-to-severe ARDS.This article briefly interprets the relevant content in order to provide clinical references for the diagnosis and treatment of ARDS patients.

Key words: Acute respiratory distress syndrome, Corticosteroids, Venovenous extracorporeal membrane oxygenation, Neuromuscular blockade, Positive end-expiratory pressure

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