Abstract:

Takotubo syndrome (TTS), also known as stress cardiomyopathy (SCM), heartbreak syndrome, apical balloon syndrome, is a transient cardiac syndrome characterized by left ventricular apical motor loss and basal systolic enhancement similar to acute coronary syndrome. As early as 1990, the Japanese scholar Sato and others reported for the first time the ECG changes of a case of chest pain with typical acute myocardial infarction, but the coronary angiography was normal, showing the characteristic left ventricular systolic state, which is similar to the round bottom and narrow mouth of the traditional Japanese Octopus basket. Subsequently, Pavin found that TTS often occurs after strong emotional stress, and suggested that TTS is significantly related to the increase of catecholamine level under stress status, thus proposed its stress characteristics. ICU patients have severe stress and severely increased catecholamine levels due to severe infections, trauma, shock and other stimuli. Therefore, SCM is not uncommon in ICU. In particular, sepsis is a common critical illness in ICU, nearly 60% patients with sepsis have cardiac dysfunction, and its pathological mechanism is similar to that of SCM. At this stage of the study, there is no clear distinction between sepsis-related cardiomyopathy and TTS.

Key words: Takotsubo cardiomyopathy, Sepsis, Intensive care units