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Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition) ›› 2021, Vol. 07 ›› Issue (02): 159-163. doi: 10.3877/cma.j.issn.2096-1537.2021.02.012

• Review • Previous Articles     Next Articles

Clinical research progress of diastolic blood pressure in predicting the progression and guiding the treatment of septic shock

Zhiwei Gao1, Jianfeng Xie2, Ling Liu2, Hui Chen2, Cong Li2, Yi Yang2,()   

  1. 1. Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine Southeast University, Nanjing 210000,China; Department of Emergency, the Affiliated Huaian NO.1 People's Hospital of Nanjing Medical University, Huai'an 223300, China
    2. Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine Southeast University, Nanjing 210000,China
  • Received:2021-02-07 Online:2021-05-28 Published:2021-08-13
  • Contact: Yi Yang

Abstract:

Even if patients with septic shock were actively resuscitated in accordance with the guidelines of the surviving sepsis campaign bundle, some patients still had low diastolic blood pressure with a mean arterial pressure ≥65 mmHg. As an indicator of vascular tension and left ventricular perfusion pressure, diastolic blood pressure reduction is closely related to the disease severity and prognosis of septic shock patients. In this manuscript, we reviewed the pathophysiological mechanism of blood pressure reduction in septic shock, the predictive value of diastolic blood pressure on the occurrence and development of septic shock, organ dysfunction and prognosis, as well as the guidance for the early use of vasopressor, providing more information for ICU physicians in management of septic shock.

Key words: Septic shock, Diastolic blood pressure, Mean arterial pressure, Vascular resistance

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