Sepsis is defined as life-threatening organ dysfunction caused by adysregulated host response to infection, considered as a major global public health problem. Though relevant studies focused on Chinese sepsis epidemiology were not comprehensive, those studies still suggested that compared with high-income countries (HICs), the incidence and mortality of sepsis in China were relatively high, the long-term outcomes were poor and the burden of sepsis was heavy. This review of the current domestic sepsis epidemiology-related studies provides research directions for the adjustment of medical and health resources and future research.